Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) is a severe drug-induced adverse fever, cutaneous eruptions, hematological abnormalities, organ dysfunction, reactivation of human herpesvirus 6 (HHV-6). Although rapid diagnosis necessary for the management DIHS/DRESS, it difficult to distinguish early phase DIHS/DRESS from other drug erup...

Drug eruption is a major problem of adverse drug reactions and may present as variform clinical manifestations. Toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP) are relatively rare severe drug eruptions. It has rarely been reported that AGEP overlaps or mimics TEN, while no purulent bullous epidermal necrolysis has been reported. The present study reports a...

Vol. 26 No. 1, 2014 141 Received September 4, 2012, Revised January 11, 2013, Accepted for publication April 2, 2013 Corresponding author: Sung Yul Lee, Department of Dermatology, Soonchunhyang University College of Medicine, 31 Suncheonhyang 6-gil, Dongnam-gu, Cheonan 330-721, Korea. Tel: 82-41-570-2270, Fax: 82-41-578-2270, E-mail: [email protected] This is an Open Access article distribu...

Mefenamic acid is a common widely prescribed drug with analgesic activity. Authors report two cases of multifocal fixed drug eruption induced by mefenamic acid. Cases were diagnosed on basis of clinical examination and histopathology of skin lesion. Only a few cases have been reported in the literature and these are the first two described in Greece.

Indian Journal of Psychiatry Volume 59, Issue 2, April-June 2017 250 Department of Oral Medicine and Radiology, Teerthanker Mahaveer Dental College and Research Centre, 1Department of Pharmacology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, 2Department of Pulmonary Medicine, Darbhanga Medical College and Hospital, Darbhanga, Bihar, India. E-mail: drvpgir...

Drug-related eruptions that appear only on intertriginous or flexural folds and in gluteal areas have recently been termed symmetrical drug-related intertriginous and flexural exanthema (SDRIFE). We report a case of a 56-year-old woman with acute erythematous rash in the intertriginous areas after treatment with the L-valine ester of acyclovir, valacyclovir. Oral-challenge tests resulted in ery...

Herbal medicine is widely used worldwide and is associated with side-effects such as skin eruptions. Herbal drugs are often produced by combining multiple crude drugs, mostly of plant origin. Determining which medi-cinal plants are associated with the herbal drugs that induce skin eruptions can therefore be difficult. This study investigated mRNA expression of several cytokines in peripheral mo...

Dermatological disorders are among the most prevalent manifestations of HIV infection/acquired immunodeficiency syndrome (AIDS). In this review, we aimed to characterize various dermatologic presentations HIV-infected patients with a detailed categorization mucocutaneous signs and symptoms, their etiopathogenic factors, clinical management. fact, cutaneous quite various, ranging from AIDS-speci...

Allergic reaction to insulin preparations seemed to have decreased since the introduction of contaminant-free, human preparations. The role of protamine sulfate in decreasing the prevalence of allergy is unclear. This study examines the causative components of insulin allergy along with the value of skin tests for diagnosis. Eleven patients with insulin allergy and 53 patients receiving insulin...

Recurrent localised inflammatory skin reactions healing with hyperpigmentation can be induced by certain drugs and are known as fixed drug eruptions. In few cases also food was described to induce these symptoms, and the term " fixed food eruptions " was coined. Fixed food eruptions are rare, the first case was reported in 1992 (1) and the term in analogy to the clinical similarities to fixed d...