Involved in many diseases such as cancer, diabetes, neurodegenerative, inflammatory and respiratory disorders, G-protein-coupled receptors (GPCRs) are among the most frequent targets of therapeutic drugs. It is time-consuming and expensive to determine whether a drug and a GPCR are to interact with each other in a cellular network purely by means of experimental techniques. Although some comput...

We conducted a questionnaire survey in order to grasp the actual conditions under which antineoplastic drugs are mixed for injection in hospitals. Questionnaires were sent to all 155 hospitals with 100 or more beds for general patients in Osaka Prefecture, Japan. The response rate was 69.0%. Mixing of antineoplastic drugs was done in 81.3% of the hospitals. The questionnaire was answered by doc...

Oral bioavailability of a drug compound is the significant property for potential drug candidates. Measuring this property can be costly and time-consuming. Quantitative structure-property relationships (QSPRs) are used to estimate the percentage of oral bioavailability, and they are an attractive alternative to experimental measurements. A data set of 217 drug and drug-like compounds with meas...

AIM Aim of this study is to determine the levels of knowledge related with drug administration and drug administration errors of nurses who care for pediatric patients. MATERIAL AND METHODS The study data were obtained from the nurses who were working in the departments of pediatrics in two education and research hospitals in the province of İstanbul and who accepted to participate in the stu...

Health care organizations considering outsourcing sterile compounding services should have a clear understanding of what they want to accomplish. Consideration should include, at the least, an internal needs assessment, a cost analysis, and a careful review of prospective compounding pharmacies. The organization should examine the potential long-term consequences of outsourcing as well as the s...

In this paper, we describe the design and integration of a three level cascaded non-deterministic finite state model of Turkish compounding into Turkish PAPPI, a comprehensive syntactic parser in the principles-andparameters(P&P) framework. Our approach is to handle compounding as an intermediate stage between morphological analysis and syntactic parsing. We discuss how the compounding machine ...

OBJECTIVES The aims of this study were to determine the frequency of prescription compounding by community pharmacists, identify factors that influence pharmacists' decisions to provide compounding services, and evaluate physicians' perspectives on prescribing medications that require compounding. METHODS The study was a cross-sectional survey administered via face-to-face structured intervie...

PURPOSE Issues surrounding pharmacy compounding as well as patient safety concerns surrounding compounding of high-risk level products are discussed. SUMMARY The practice of traditional pharmacy compounding is an established activity of pharmacists that serves a vital function to meet the prescribed medical needs of individual patients. However, legal and regulatory debate concerning the over...