OBJECTIVE Traumatic brain injury (TBI) is a major brain injury type commonly caused by traffic accidents, falls, violence, or sports injuries. To obtain mechanistic insights about TBI, experimental animal models such as weight-drop-induced TBI in rats have been developed to mimic closed-head injury in humans. However, the relationship between the mechanical impact level and neurological severit...

traumatic brain injury (tbi) is an important clinical problem in the worldwide and especially due to breaking driving rules in iran, but undesirable consequences of trauma can persist for the rest of patient’s life. we investigated the effect of a novel weight drop model of tbi on incidence of seizure 2 weeks after tbi. in this regard, 21 male wistar rat weighted 250-300 gr randomly were divide...

Tissue, organ and organoid cultures provide suitable models for developmental studies, but our understanding of how the organs are assembled at the single-cell level still remains unclear. We describe here a novel fixed z-direction (FiZD) culture setup that permits high-resolution confocal imaging of organoids and embryonic tissues. In a FiZD culture a permeable membrane compresses the tissues ...

Concrete structures have been widely used for many years to resist impact loads. Steel–concrete composite may be considered efficient in the emerging modern construction field. Hence, main objective of this research was study behavior steel concrete slabs with different shear connectors and compare them conventional slabs. Seven specimens dimensions 500 × 50 mm were cast, which included plain c...

Victims of minimal traumatic brain injury (mTBI) do not show clear morphological brain defects, but frequently suffer lasting cognitive deficits, emotional difficulties and behavioral disturbances. In the present study we adopted a non-invasive closed-head weight-drop mouse model to produce mTBI. We examined the effects of 20, 25, or 30 g weight drop 7, 30, 60 and 90 days following injury on mi...

Collisions of bubble jets have been experimentally studied in normal gravity conditions. The experimental setup, designed for a future use in a low gravity environment, allows the control of the impact angle between jets, bubble size and velocity. Individual bubble properties and the whole jet structure are analyzed from the images recorded. We present results on the role played by the impact a...