The CNS has long been considered an immune-privileged site as tissues grafted into the CNS are not rejected as they are in other tissues (Medawar, 1948; Billingham and Boswell, 1953; Barker and Billingham, 1977). An avalanche of evidence now suggests that this privilege is not absolute, as robust immune responses can occur in the CNS during infections and autoimmune diseases such as multiple sc...

The CNS has long been considered an immune-privileged site as tissues grafted into the CNS are not rejected as they are in other tissues (Medawar, 1948; Billingham and Boswell, 1953; Barker and Billingham, 1977). An avalanche of evidence now suggests that this privilege is not absolute, as robust immune responses can occur in the CNS during infections and autoimmune diseases such as multiple sc...

UNLABELLED BACKGROUND The emigration of skilled nurses from the Philippines is an ongoing phenomenon that has impacted the quality and quantity of the nursing workforce, while strengthening the domestic economy through remittances. This study examines how the development of brain drain-responsive policies is driven by the effects of nurse migration and how such efforts aim to achieve mind-sh...

We investigated the frequency dependences of Y22 of FDSOI MOSFETs, in which the drain current response delay is observed for the first time. Short channel FD-SOI devices operating in linear region show significant drain current response delay. It is confirmed that FD-SOI MOSFET’s RF behavior can be well reproduced with the proposed model including the drain current response delay.

Although knee joint arthroscopy is one of the most frequently performed surgical procedures worldwide, there is no consensus on how to apply a drain in the joint if it is decided to use one. Therefore we describe a simple technique to safely apply a drain intra-articularly under full arthroscopic control, avoiding placement of the drain through the arthroscopic portal.

Opportunity is the driving force of migration. Unsatisfied demands for higher education and skills, which have been created by the knowledge-based global economy, have generated unprecedented opportunities in knowledge-intensive service industries. These multi-trillion dollar industries include information, communication, finance, business, education and health. The leading industrialized natio...

This paper proposes and demonstrates the extraction of MOSFET threshold voltage, source-drain resistance, gate field mobility reduction factor, and transistor gain factor from the measurement of the small-signal source-drain conductance of a transistor as a function of dc gate bias with zero dc drain bias. The theory is based on the analytical model that includes the effects of source-drain res...

BACKGROUND Perioperative blood loss is still an unsolved problem in total knee arthroplasty (TKA). The efficacy of the preoperative use of tranexamic acid (TXA) plus drain-clamping to reduce blood loss in TKA has been debated. This meta-analysis aimed to illustrate the efficacy of TXA plus drain-clamping to reduce blood loss in patients who underwent a TKA. METHODS In February 2017, a systema...