Several weeks after the test, Mr Jones learned that he tested positive for a mutation and was sent a form letter stating that “men with this mutation have a 6 percent chance of developing breast cancer and a 7 percent chance of developing prostate cancer before age 70.” Concerned about his results, he went to see Dr Seelinn to find out what he should do with this new information. As he handed D...

Scientific objective: In a recent blog post Dr Andrew Thorburn 1asks why many published discoveries cannot be replicated. He summarizes examples from Dr Glenn Begley (Vice President for oncology at Amgen) that show how Amgen has been unable to reproduce many high-profile discoveries. Dr Thorburn raises the possibility that ‘sloppy science’ may partly explain our inability to measurably improve ...

Power companies such as Southern California Edison (SCE) uses Demand Response (DR) contracts to incentivize consumers to reduce their power consumption during periods when demand forecast exceeds supply. Current mechanisms in use offer contracts to consumers independent of one another, do not take into consideration consumers’ heterogeneity in consumption profile or reliability, and fail to ach...

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This is an admirable little monograph from an admirable series of little volumes. Not merely the layman, but also the medical man and the research worker will be interested in Dr Singers well written, carefully compiled and useful little book. Commencing with ancient days he reviews in turn Aristotle s viewswho regarded the heart as the seat of intelligence and the source of bodily heat; the vi...

Author Disclosure Drs Hellström-Westas, Rosén, and de Vries have been involved in development or testing of the instruments (BrainZ [BrainZ Instruments Ltd, Auckland, New Zealand], Olympic 6000 [Olympic Medical, Seattle, Washington], and Nervus Monitor [Viasys, Nicolet Biomedical, Madison, Wisconsin]) from which records are shown in this article. None has an economic interest in the production ...