نتایج جستجو برای: doxycycline hyclate

تعداد نتایج: 5120  

Journal: :QJM: An International Journal of Medicine 2018

Journal: :caspian journal of internal medicine 0
seyed mohammad alavi leila alavi

background: the treatment of human brucelosis is controversial. the purpose of this study was to search published clinical trial papers to provide a simple and effective treatment in brucellosis. methods: many studies on brucellosis treatment in a twenty- year span from 1993 to 2012 were searched in pubmed, web of science (isi), scopus, google scholar, magiran, iranmedex and sid. the studies th...

2014
Wei Wu Li-hua Yu Bei Ma Ming-juan Xu

BACKGROUND Detecting a new effective and hypotoxic anticancer drug is an emerging new strategy for cancer chemotherapy. Doxycycline (DC) is a kind of antibiotics but also inhibits tumorigenesis. METHODS MTT and cell invasion assay, flow cytometry, western-blot analysis and nude mice were used to investigate the effects and underlying mechanisms of doxycycline on epithelial ovarian cancer cell...

Journal: :The American journal of tropical medicine and hygiene 2001
W R Taylor H Widjaja T L Richie H Basri C Ohrt Tjitra E Taufik T R Jones K C Kain S L Hoffman

Combination therapy is one method of overcoming the global challenge of drug-resistant Plasmodium falciparum malaria. We conducted a hospital-based 28-day in vivo test comparing chloroquine/doxycycline to chloroquine or doxycycline alone for treating P. falciparum and Plasmodium vivax malaria in Irian Jaya, Indonesia. Eighty-nine patients with uncomplicated falciparum malaria were randomized to...

2013
Jeffrey C. Hoyt Janelle G. Ballering John M. Hayden Richard A. Robbins Carl T. Hayden

Doxycycline is an antibiotic that possess anti-inflammatory properties. These anti-inflammatory properties make doxycycline an attractive candidate for possible treatments for a variety of common chronic obstructive airway diseases. Interleukin-8 (IL-8) is a major inflammatory chemokine and a powerful chemoattractant for both neutrophils and monocytes. We hypothesized that doxycycline might exe...

2015
Ho Yin Ng Brian Gregory George Oliver Janette Kay Burgess Vera P Krymskaya Judith Lee Black Lyn M Moir

Lymphangioleiomyomatosis (LAM) is associated with dysfunction of the tuberous sclerosis complex (TSC) leading to enhanced cell proliferation and migration. This study aims to examine whether doxycycline, a tetracycline antibiotic, can inhibit the enhanced migration of TSC2-deficient cells, identify signalling pathways through which doxycycline works and to assess the effectiveness of combining ...

Journal: :Antimicrobial agents and chemotherapy 2005
Jean-Marc Rolain Areen Boulos Marie-Noëlle Mallet Didier Raoult

Endocarditis is the major clinical manifestation of chronic Q fever. Although doxycycline along with hydroxychloroquine remains the mainstay of medical therapy for Q fever endocarditis, there are wide variations in the rapidity of the patient's decline of antibody levels during such therapy. We undertook a retrospective examination of whether there was any correlation between the ratio of serum...

2010
Joseph D. Turner Nicholas Tendongfor Mathias Esum Kelly L. Johnston R. Stuart Langley Louise Ford Brian Faragher Sabine Specht Sabine Mand Achim Hoerauf Peter Enyong Samuel Wanji Mark J. Taylor

BACKGROUND The risk of severe adverse events following treatment of onchocerciasis with ivermectin in areas co-endemic with loiasis currently compromises the development of control programmes and the treatment of co-infected individuals. We therefore assessed whether doxycycline treatment could be used without subsequent ivermectin administration to effectively deliver sustained effects on Onch...

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