Carcinoma of prostate (CaP) is the second most frequent malignant tumor occurring in men in Europe. Currently there is discussion on a wide range of potential CaP markers.One of them—nonprotein amino acid sarcosine, also known as N-methylglycine was chosen as a challenge for the development of microfluidic system with isolation by modified paramagnetic microparticles. Therefore, the aim of this...

Reduced, S-aminoethylated porcine ribonuclease was subjected to tryptic hydrolysis. A sequence of fractionation steps that included gel filtration and chromatography over SE-Sephadex C-50, Dowex 50-X2, and Dowex l-X2 afforded a series of glycopeptide fractions which were recognized to derive from three separate regions of the molecule. Heterogeneity of the attached polysaccharide chains preclud...

We present performance data for low-noise free-running high-rate photon counting method for space optical communication and ranging. NASA GSFC is testing the performance of two types of novel photon-counting detectors 1) a 2x8 mercury cadmium telluride (HgCdTe) avalanche array made by DRS Inc., and a 2) a commercial 2880-element silicon avalanche photodiode (APD) array. We successfully measured...

Treatment of keratosulfates with alkali leads to the formation of 3,6-anhydroglucosaminyl groups in high yield. A similar reaction takes place with heparin and heparitin sulfate, though to a lesser extent. The anhydrosugar was isolated and compared with synthetic 3,6-anhydroglucosamine. The isolated compounds were identical in ion exchange chromatography in the amino acid analyzer and on Dowex ...

Fermentation of purines by Clostridium acidiuirici was observed in early studies (Barker and Beck, 1941) to yield acetate, carbon dioxide, ammonia, glycine and formate. The formation of glycine and formate was confirmed more recently by Radin and Barker (1953), and Bradshaw and Beck (1953). Sagers and Beck (1956) have demonstrated, as was first suggested by Radin and Barker (1953), that L-serin...

Laboratory tests and a field validation experiment were performed to evaluate anion exchange resins for uranium sorption and desorption in order to develop a uranium passive flux meter (PFM). The mass of uranium sorbed to the resin and corresponding masses of alcohol tracers eluted over the duration of groundwater installation are then used to determine the groundwater and uranium contaminant f...