The variation of the haptogIobins of human plasma was shown by Smithies (1955) and Smithies & Walker (1956, 1956) to be a Mendelian trait controlled by two alleles. These two alleles, Hpl and Hp2, co-exist generally in human populations, and their relative proportions exhibit geographic variation. Additional haptoglobin variants have been detected, but their genetic relationships to the first t...

Dr. Pierre A. de Viragh, Service de dermatologie, Centre hospitaller universitaire, CH-1011 Lausanne (Switzerland) The case report of Komura and Tani [1] on a hair follicle nevus provides the opportunity to raise the question whether this hamar-toma is really an entity of its own. There are some indications that the hair follicle nevus could be a well-differentiated trichofollicu-loma cut at it...

A recent article in EMBO reports by Bornmann & Daniel (2009) commented that “the h index [...] is already regarded as the counterpart to the [impact factor]”. Indeed, the h index (Hirsch, 2005) is increasingly being used to evaluate the achievements of individual scientists, and major citation databases—such as the Scientific Citation Index (SCI; Thomson Reuters, New York, NY, USA) and Scopus (...

Human immunodeficiency virus type 1 (HIV-1) genotypic resistance testing is frequently done to help select therapy for HIV-1-infected persons. The manual interpretation of such assays is difficult, because a large number of reverse transcriptase (RT) and protease drug resistance mutations interact and emerge in complex patterns. Several computerized interpretation algorithms have been developed...

Lunt (1) and Mainil (2) emphasize the importance of continued research into the scope, nature and motivations for cross border care within Europe. Understanding patient mobility in the rapidly changing environment and turbulent movements is crucial in the consideration of accessible healthcare provision. Crossing the border or travelling far destinations in order to obtain healthcare, medical s...

Say what you like about the NHS, but you have to admit it’s extraordinarily good at setting obstacles in the way of care. Sometimes it seems that the entire system is built on the principles of the medieval castle, with a series of redoubts, moats, and stout stone walls designed to defend against unwelcome intruders—that is to say, patients. Gatekeeping is the watchword. Today even the gatekeep...

In his impressive new volume, Jon Stewart sets out to introduce Hegel's Lectures on the Philosophy of Religion within broader context Enlightenment's criticism religion and philosophy. The book expounds reaction what he perceived as ubiquitous theology by subjectivity, embodied in thinkers such Rousseau, Jacobi, Schleiermacher. this context, according Stewart, Hegel sought defend Christianity a...

The starting point of this paper is the assumption that North Korea is de facto a well defined nation-state with a national economy and inhabited by individuals that bear the same basic economic and social characteristics as individuals elsewhere. Despite the obvious specifics of the economic system and the institutional structure of that country, standard economic theory should be applicable t...

Data mining extracts hidden information from a database that the user did not know existed. Biclustering is one of the data mining technique which helps marketing user to target marketing campaigns more accurately and to align campaigns more closely with the needs, wants, and attitudes of customers and prospects. The biclustering results can be tuned to find users’ browsing patterns relevant to...

A. McGEHEE HARVEY ans SUSAN L. ABRAMS, "For the welfare of mankind". The Commonwealth Fund and American medicine, Baltimore, Md., and London, Johns Hopkins University Press, 1986, 8vo, pp. xiii, 696, £26.50. Histories of philanthropic bodies are notoriously difficult to produce without being boring to all those not directly concerned, such as trustees, staffs, advisers, and, ofcourse, recipient...