Aims Pelvic radiotherapy adds significantly to the curative treatment of many pelvic malignancies. However, this cure comes at a cost for patients, where late bowel toxicities, such as faecal incontinence, urgency and diarrhoea, adversely affect quality life. Despite implementation advanced techniques in centres, there are deficiencies our knowledge how make best use these minimise with dose–vo...

Introduction: Field-in-Field (FIF) and Intensity Modulated Radiation Therapy (IMRT) are two advanced radiation therapy planning techniques. Both of them are being used to achieve the same two related aims which are, to expose the targeted tumor to the full radiation dose and to spare the nearby normal tissues (or organs) from being exposed to high amounts of radiation more than its tolerance do...

Intensity-modulated proton therapy (IMPT) is expected to improve treatment results with fewer side effects than other proton therapies. The purpose of this study was to evaluate the tumor sites for which IMPT was effective under the same beam calculation conditions by planning IMPT for typical cases treated with passive scattering proton therapy (PSPT). We selected 16 cases of nasal cavity, lun...

Recently, volumetric-modulated arc therapy (VMAT) has demonstrated the ability to deliver radiation dose precisely and accurately with a shorter delivery time compared to conventional intensity-modulated fixed-field treatment (IMRT). We applied the hypothesis of VMAT technique for the treatment of thoracic esophageal carcinoma to determine superior or equivalent conformal dose coverage for a la...

Abstract Background Cancer is one of the leading causes death worldwide. According to GLOBOCAN estimates, there were 341,831 deaths from cervical cancer in 185 countries 2020. The aim this study was compare equieffective dose (EQD 2 ) at Gy per fraction by using volume histograms (DVHs) derived external beam radiotherapy (EBRT) and high-dose rate brachytherapy (HDR-BRT) treatment plans used rad...

The purpose of this study was to evaluate the applicator-guided volumetric-modulated arc therapy (AGVMAT) solution as an alternative to high-dose-rate brachytherapy (HDR-BRT) treatment of the vaginal vault in patients with gynecological cancer (GC). AGVMAT plans for 51 women were developed. The volumetric scans used for plans were obtained with an implanted CT-compatible vaginal cylinder which ...

Radiotherapy (RT) is the most widely used cancer treatment modality that plays a pivotal role in the management of wide variety of cancers and malignancies. About 50% of all cancer patients receive radiation treatment during the course of their disease (1). Although by advances in medical technologies the final goal of RT, deliver the highest radiation dose to the tumor volume and sparing surro...

Introduction: A study was performed to evaluate radiation dose distribution and dose gradient around cylindrical applicators for high-dose-rate (HDR) brachytherapy systems with 192Ir, 60Co brachytherapy source applied for rectal and vaginal cancers treatments.   Materials and Methods: Two additional computed tomography (CT) based plans were generated using a ...

PURPOSE At present, techniques of 4D dose verification in radiation therapy for lung cancers associated with respiratory motion are very limited, due to either lack of patient anatomy or breathing information. The aim of this study is to develop a 4D dose verification technique based on XCAT phantom which incorporates both patient anatomy and respiratory mechanics. MATERIALS AND METHODS The 4...