background and objectives: hepatitis e virus (hev) is a major public health concern in developing countries. hev transmission occurs primarily by the fecal-oral route. it has also been reported that blood donors are potentially able to cause transfusion-associated hepatitis e in endemic areas. this study aimed to determine the seroprevalence of hev infection among volunteer blood donors in cent...

purpose: to determine bacterial contamination of corneas and corneal storage media provided from the eye bank of i.r. iran to rasool akram medical center. methods: this descriptive study was performed on 70 corneoscleral rims and corneal storage media. one milliliter of corneal storage media and the corneoscleral rim were sent to microbiology laboratory at the time of penetrating keratoplasty a...

PURPOSE To determine if there is a difference in antibiotic sensitivity to coagulase-negative Staphylococcus (CNS) cultured from the host versus the donor cornea at the time of corneal transplantation. Then to apply this knowledge to preoperative preparation of patients undergoing eye surgery. METHOD A total of 923 donor corneas stored in Optisol and 895 host corneas with no preoperative anti...

We developed cell-free implants, comprising carbodiimide crosslinked recombinant human collagen (RHC), to enable corneal regeneration by endogenous cell recruitment, to address the worldwide shortage of donor corneas. Patients were grafted with RHC implants. Over four years, the regenerated neo-corneas were stably integrated without rejection, without the long immunosuppression regime needed by...

PURPOSE To validate tissue quality parameters for donor corneas designated for emergency grafting for corneal graft survival. METHODS In a longitudinal cohort follow-up study, 131 emergency penetrating grafts were studied. Grafts were performed with a pool of organ-cultured donor corneas designated for emergency grafting and prepared for immediate use with all safety tests performed. Assignat...

Three new triarylborane conjugated dicyanovinyl chromophores (Mes2B-π-donor-DCV); donor: N-methyldiphenylamine () and triphenylamine ( and [with two BMes2 substitutions]) of type A-D-A (acceptor-donor-acceptor) are reported. Compounds exhibit intense charge transfer (CT) absorption bands in the visible region. These absorption peaks are combination CT bands of the amine donor to both the BMes2 ...

OBJECTIVE To determine whether graft survival over a 5-year follow-up period using corneal tissue from donors older than 65 is similar to graft survival using corneas from younger donors. DESIGN Multicenter prospective, double-masked, controlled clinical trial. PARTICIPANTS One thousand ninety subjects undergoing corneal transplantation for a moderate-risk condition (principally Fuchs' dyst...

Background: Couples seeking assisted reproductive donation procedures are faced with complex challenges throughout their treatment which can have important psychological impacts on their life. Selecting a suitable donor is one of the hardest decisions they will ever make. This study was carried out to provide an in-depth description of the experiences of couples in relation to donor selection. ...

We have utilized H-2 specific antisera from congenic resistant donor recipient combinations to localize H-2 antigens in tissue sections using the indirect immunofluorescent technique. H-2 specific immunofluorescence is observed in spleen, kidney, and liver sections: however, especially with liver sections, there are cases in which the expected specific stain is weak or absent. In addition to mi...

Over the past ten years, corneal transplantation surgical techniques have undergone revolutionary changes. Since its inception, traditional full thickness corneal transplantation has been the treatment to restore sight in those limited by corneal disease. Some disadvantages to this approach include a high degree of post-operative astigmatism, lack of predictable refractive outcome, and disturba...