The Caenorhabditis elegans sex determination gene, tra-2, is translationally regulated by elements in the 3'-untranslated region called TGEs. TGEs govern the translation of mRNAs in both invertebrates and vertebrates, indicating that this is a highly conserved mechanism for controlling gene activity. A factor called DRF, found in worm extracts binds the TGEs and may be a repressor of translatio...

BACKGROUND Poisson regression is routinely used in occupational and environmental epidemiology. For typical Poisson regression analyses, person-time and events are tabulated by categorising predictor variables that were originally measured on a continuous scale. In order to estimate a dose-response trend, a researcher must decide how to categorise exposures and how to assign scores to exposure ...

We have previously shown that the gld autoimmune syndrome is suppressed in lethally irradiated gld mice reconstituted with a mixture of normal and gld bone marrow (BM). Furthermore, in vivo depletion of normal Thy-1+ cells restores lymphoproliferation and autoantibody production in such chimeras, suggesting that T cells bearing Fas ligand are responsible for correcting the gld defect. In this s...

BACKGROUND An efficient operating room needs both little underutilised and overutilised time to achieve optimal cost efficiency. The probabilities of underrun and overrun of lists of cases can be estimated by a well defined duration distribution of the lists. OBJECTIVE To propose a method of predicting the probabilities of underrun and overrun of lists of cases using Type IV Pearson distribut...

In percentile method, percentiles of the diameter distribution are predicted with a system of models. The continuous empirical diameter distribution function is then obtained by interpolating between the predicted values of percentiles. In Finland, the distribution is typically modelled as a basal-area weighted distribution, which is transformed to a traditional density function for application...

Let X ⊂ PK be Drinfeld’s upper half space over a finite extension K of Qp. We construct for every GLd+1-equivariant vector bundle F on PK , a GLd+1(K)equivariant filtration by closed subspaces on the K-Fréchet H0(X ,F). This gives rise by duality to a filtration by locally analytic GLd+1(K)-representations on the strong dual H0(X ,F)′. The graded pieces of this filtration are locally analytic i...

Grapevine leafroll disease (GLD) is an economically important virus disease affecting wine grapes (Vitis vinifera L.), but little is known about its effect on wine chemistry and sensory composition of wines. In this study, impacts of GLD on fruit yield, berry quality and wine chemistry and sensory features were investigated in a red wine grape cultivar planted in a commercial vineyard. Own-root...