Similarity in Dissolution behavior of drugs has long been sought from the percpective of both bioavailability and quality control considrations. The objective of this study was to apply several profile comparison to dissolution data of three different batches of Indomethacin (SR) which two of them were German products as the refernce batches. Dissolution was performed using the United States Ph...

introduction the iran has vast areas of karst landforms due to the relatively high carbonaceous rocks deposited during different geologic eras. karst landforms are noteworthy for investigation from many aspects. the primary importance of these regions is the considerable amount of underground water stored in karst formations. these reserves are favorable, both in quality and quantity, as natura...

The dissolution dynamics of a NaCl nanocrystal in liquid water was studied using molecular dynamics simulations. The dissolution process was found to start with a Cl(-) ion at a corner site, followed by a Na(+) ion nearby. Both show directional preference in the dissolution path. An ion sequence with alternating charge, i.e., Cl(-), Na(+), Cl(-), Na(+), etc. was found to dominate the dissolutio...

The objective of present work is to investigate the enhancement of dissolution profile for oral delivery of Fexofenadine Hydrochloride (FH) through solid dispersion (SD) technique by the method of solvent evaporation. The SD was prepared by using ethanol as a solvent. Tablets were formulated containing solid dispersion of FH and compared with tablets of same formula without solid dispersion of ...

In the context of the study of the wet creep of plasterboards, we have performed digital holographic interferometry measurements of the dissolution of gypsum of various quarries in water and in aqueous solutions of salts inhibiting dissolution, and of the dissolution of anhydrite in water. This technique is carried out in still water and permits to observe directly the reacting solid-liquid int...

The purpose of this article was to prepare and optimize the ingredients of Repaglinide tablets. The impacts of ingredients (diluents, disintegrants and lubricants) content on tablets were evaluated. The optimum prescription contained Repaglinide, meglumine, poloxamer, MCC, maize starch, PVPP, magnesium stearate and appropriate PVP K30.The tablets were evaluated by Carr’s index, hardness, friabi...

The present work concerns with an investigation on the solubility of cis,cis-muconic acid dissolution in different polar solvents by characterizing and modeling the dissolution as a function of temperature. Water, ethanol, 2-propanol and acetic acid have been investigated as solvents in the range temperatures from a 298.15 to 348.15 K. Owing to the absence of cis,cis-muconic acid solubility...

Two studies investigated the process by which individuals in nonmarital romantic relationships characterized by low commitment move toward enacting leave behaviors. Predictions based on the behavioral, goal, and implementation intention literatures were tested using a measure of dissolution consideration developed for this research. Dissolution consideration assesses how salient relationship te...

The present work deals with the comparison of in vitro dissolution profiles of fenofibrate liquisolid tablet formulations with those of marketed fenofibrate tablets, and the application of statistical methods to evaluate each method for its usefulness. The methods used to study dissolution profile comparison include Model independent method (Similarity factor, f2); Model dependent methods (Zero...

We explore theoretically the controls on dissolution of salt A, in an under-saturated brine of salts A and B. We show that, as the concentration of B increases, the dissolution rate of A decreases, for brine of given temperature. We also show that there is a sharper decrease in dissolution rate with increasing concentration, for concentrations of B above a critical value, where B limits the equ...