Background.  Expert panel of physicians and nonphysicians, all expert in intrathecal (IT) therapies, convened in the years 2000 and 2003 to make recommendations for the rational use of IT analgesics based on the preclinical and clinical literature known up to those times, presentations of the expert panel, discussions on current practice and standards, and the result of surveys of physicians us...

One of the main features of the immune response to M. Tuberculosis is the formation of an organized structure called granuloma. It consists mainly in the recruitment at the infectious stage of macrophages, highly differentiated cells such as multinucleated giant cells, epithelioid cells and Foamy cells, all these cells being surrounded by a rim of lymphocytes. Although in the first instance the...

A 66-year-old man with human immunodeficiency virus (HIV) infection was admitted for treatment of Pneumocystis pneumonia. Upon admission, a tumor mass adjacent to the thoracic descending aorta was revealed on computed tomography. Histology revealed an exudative granuloma with histiocytes packed with numerous acid-fast bacilli. Mycobacterium avium was isolated from the tissue. A genetic examinat...

Invasive intracranial aspergillosis is a rare disease with high morbidity and mortality that occurs most commonly in immunosuppressed patients. However, intracranial Aspergillus infections have also been reported in immunocompetent hosts after brain trauma or neurosurgery. Neurosurgical intervention combined with aggressive antifungal treatment is effective in treating cerebral aspergillus gran...

Disseminated granuloma annulare (DGA) is an inflammatory disease that tends to follow a chronic course and is resistant to multiple treatments. We report the case of a 80-year-old woman with asymptomatic lesions that had developed 3 years earlier. The lesions initially developed on the arms, later spreading to the abdomen, back, and legs, and improved during the summer months. The patient had u...

Extramedullary plasmacytoma (EMP) is the term for plasma cell tumours which present outside of bone.The plasma cell lesions affecting the head and neck are multiple myeloma, EMP, plasma cell granuloma, and solitary plasmacytoma. EMP has been rarely met in the form of multiple lesions (10 per cent) (1). EMP could be staged according to the spread of the disease: Stage I is disease confined to on...

Le syndrome de Melkersson-Rosenthal est une entité clinique rare, définie par la triade oedème oro-facial, paralysie faciale récurrente et langue plicaturée. Cette triade peut être incomplète ou apparaître de manière différée dans le temps. Le diagnostic est confirmé par l'histologie. Il s'agit d'une entité complexe dont la prise en charge est difficile en raison de son polymorphisme clinique e...

Cladophialophora bantiana is a neurotropic dematiaceous fungus which only rarely affects the skin. We report a case of disseminated cutaneous phaeohyphomycosis caused by Cladophialophora bantiana in an immunocompromised female who presented with multiple pyogenic granuloma-like nodules, dermatophytosis-like plaque, and subcutaneous cysts on the upper and lower extremities without systemic invol...

Disseminated granuloma annulare (DGA) is an inflammatory disease that tends to follow a chronic course and is resistant to multiple treatments. We report the case of a 80-year-old woman with asymptomatic lesions that had developed 3 years earlier. The lesions initially developed on the arms, later spreading to the abdomen, back, and legs, and improved during the summer months. The patient had u...