A 30-year-old man with no significant medical history, who had been working his entire life as a gold miner in rural Colombia, came to the infectious disease outpatient clinic at our institution with a two-month history of high spiking fevers, generalized lymphadenopathy (Figure 1), right lower quadrant pain, and vertigo. He did not report any weight loss or night sweats. He also reported heada...

Disseminated Coccidioidomycosis To the Editor: Coccidioidomy-cosis, an infection caused by the dimorphic fungus Coccidioides immi-tis, is endemic in the southwestern United States, parts of Mexico, and Central and South America (1). Patients with C. immitis infection may have chronic pneumonia, fungemia, and extrapulmonary dissemination to skin, bones, meninges, and other body sites. The clinic...

hydatid disease is the most common infections worldwide, but it rarely involves multiple organs. herein, a 12-year-old boy is presented, who was admitted to children's medical center, tehran university of medical sciences, tehran, iran with symptoms of irritability, sleepless, and weak­ness of the extremities. patient's brain computed tomography (ct) scan with contrast media showed large multil...

hepatosplenic candidiasis is a fungal infection, which mostly affects patientswith hematologic malignancies such as leukemia. the pathogenesis of thisinfection is not clear yet, and the liver is the most commonly affected organ.diagnosis of hepatosplenic candidiasis can be only established via biopsy,since computed tomography (ct) scan, ultrasonography, and magneticresonance imaging (mri) yield...

Neonatal herpes simplex virus (HSV) infection is a devastating disease with high mortality, particularly when disseminated. Studies in adults and children suggest that susceptibility to encephalitis (HSE) may represent phenotypes for inborn errors toll-like receptor 3 (TLR3) signaling. However, the genetic basis of neonatal HSV including disseminated remains unknown. To test hypothesis variants...

A 23-year-old woman presented with a 1-month history of headache, vomiting, recurrent episodes of syncope, weight gain, and leg pain. A physical examination revealed several subcutaneous nodules on the patient’s face and trunk. Exophthalmos, fundal hemorrhage, neck rigidity, and a hypertrophic appearance of the thigh and calf muscles were also noted. Magnetic resonance imaging (MRI) of the head...

Lobomycosis, also known as Jorge Lobo's disease, is a granulomatous, chronic fungal disease that involves the skin and subcutaneous tissue. The disease has been reported in South American, Central and North American countries, being particularly frequent in the Brazilian Amazon region. We report a case of disseminated lobomycosis in an 86 year-old Brazilian woman with a 55-year history of disse...

The authors report an unusual case of disseminated tungiasis in a 52-year-old patient living in the city of Campo Grande, state of Mato Grosso do Sul, who had crusted-papular-nodular lesions located in feet, hands, and right thigh. Diagnosis was confirmed by dermoscopy and anatomopathological examination.