Endoscopic scoring systems in Crohn's disease and ulcerative colitis aim to translate the assessment of mucosal disease activity into a quantified value. This value seeks to provide a clear, objective record of the endoscopic mucosal severity, which can then be used to guide medical management decisions. The primary driver of all endoscopic indices, however, is to define a scale of responsivene...

pemphigus is a rare autoimmune blistering disease with different phenotypes. the evaluation of therapeutic interventions requires a reliable, valid and feasible to use measurement. however, there is no gold standard to measure the disease activity in clinical trials. in this study we aimed to introduce the pemphigus vulgaris activity score (pvas) measurement and to assess the convergent validit...

background: rheumatoid arthritis (ra) is a chronic, systemic, inflammatory disease with autoimmune etiology, characterized by synovial inflammation and destruction of joint cartilage and bone. there are controversial data about the profile of interleukin-17 (il-17a), interleukin-4 (il-4), and interferon-gamma (infî³), indicating in some studies the key role of il-17, while in others the th1 cyt...

background: cardiovascular disease is a major cause of death throughout the world. the aim of this study was to as­sess the prevalence of overweight/obesity, central obesity, hypertension and dyslipidemia, as well as dietary factors contribut­ing to the development of dyslipidemia among middle-aged women. methods: the research design of the present study was a population-based cross-sectional s...

indirect immunofluorescence (iif) has been used to identify and measure autoantibody levels in pemphigus vulgaris but data about relationship between clinical severity of disease and antibody titers by iif have been conflicting. we conducted this cross-sectional study to correlate the severity of oral and/or cutaneous involvement in patients with pemphigus vulgaris based on pemphigus area and a...

conclusions exercise test performance was affected by lower quality of life and lower physical activity after lt. with the exception of hypertension, well known factors that affect the risk of coronary artery disease had no effect on the exercise test results. objectives this study examined potential relationships between physical activity, health-related quality of life (hrqol), risk factors f...