UNLABELLED One of the challenges in PET/MRI is the derivation of an attenuation map to correct the PET image for attenuation. Different methods have been suggested for deriving the attenuation map from an MR image. Because the low signal intensity of cortical bone on images acquired with conventional MRI sequences makes it difficult to detect this tissue type, these methods rely on some sort of...

Image segmentation plays an important role in medical image processing. The aim of conventional hard segmentation methods is to assign a unique label to each voxel. However, due to the limited spatial resolution of medical imaging equipment and the complex anatomic structure of soft tissues, a single voxel in a medical image may be composed of several tissue types, which is called partial volum...

MR images are known to be distorted because of both gradient nonlinearity and imperfections in the B0 field, the latter caused either by an imperfect shim or sample-induced distortions. This paper describes in detail a method for correcting the gradient warp distortion, based on a direct field mapping using a custom-built phantom with three orthogonal grids of fluid-filled rods. The key advance...

BACKGROUND AND PURPOSE Administration of contrast material before proton MR spectroscopy may allow more accurate placement of the volume of interest, particularly in tumors; yet, some data have suggested that contrast material may alter the results of MR spectroscopy. To determine the validity of this contention, we performed pre- and postcontrast MR spectroscopy in patients with brain tumors a...

Objectives The aim of this in vitro study was to evaluate how a deviation from the horizontal plane, affects the image quality in two different CBCT-devices. Methods A phantom head SK150 (RANDO, The Phantom Laboratory, Salem, NY, USA) was examined in two CBCT-units: Accuitomo 80 and Veraviewepocs 3D R100 (J. Morita Mfg. Corp. Kyoto, Japan). The phantom head was placed with the hard palate par...

conclusion considering the similar diagnostic efficacy of all voxel sizes, 300 µm voxel size can be used with adequate efficacy for detection of external root resorption defects with minimal patient radiation dose and the shortest scanning time. background selecting a voxel size that yields minimal radiation dose with no significant compromise of the diagnostic accuracy of cone beam computed to...

BACKGROUND Full Monte Carlo (MC)-based SPECT reconstructions have a strong potential for correcting for image degrading factors, but the reconstruction times are long. The objective of this study was to develop a highly parallel Monte Carlo code for fast, ordered subset expectation maximum (OSEM) reconstructions of SPECT/CT images. The MC code was written in the Compute Unified Device Architect...

PURPOSE In this work, we propose a new method of calibrating cone beam computed tomography (CBCT) data sets for radiotherapy dose calculation and plan assessment. The motivation for this patient-specific calibration (PSC) method is to develop an efficient, robust, and accurate CBCT calibration process that is less susceptible to deformable image registration (DIR) errors. METHODS Instead of m...

This note summarizes a technique that uses tractography to drive the local fiber model estimation. Existing techniques use independent estimation at each voxel so there is no running knowledge of confidence in the estimated model fit. We formulate fiber tracking as recursive estimation: at each step of tracing the fiber, the current estimate is guided by the previous. To do this we perform trac...

Segmentation of tubular structures like blood vessels and airways in 3D volume data is of vital interest for medical applications like diagnosis and surgical planning. The aim of this diploma thesis is to facilitate the efficient analysis of vessels by developing an automatic segmentation method. First, the method uses a vessel detection filter, which is based on a novel multiscale medialness f...