Regulatory factors and pathophysiological consequences of microbial ethanol oxidation and acetaldehyde production in the digestive tract

BACKGROUND Cancer in patients with cystic fibrosis (CF), the most common genetic disorder in Caucasians, has been a rare event. However, more patients now reach adulthood, and more patients undergo organ transplantation-factors associated with an increased cancer risk. Our aim was to assess the risk of cancer in nontransplanted and transplanted CF patients. METHODS We followed 28 858 patients...

A micro total bioassay system that mimics physiological processes was developed as a means of evaluating orally administered drugs. A new feature accounting for gastrointestinal digestion was added to the previous system, which consists of microintestine, microliver, and target components. The artificial micro-gastrointestinal tract employs synthetic digestive juices. The system could correc...

Ventilator-associated pneumonia usually originates from the patient's oropharyngeal microflora. In selective digestive decontamination, topical antibiotics are applied to the oropharynx and stomach for prevention of pneumonia and other infections, possibly reducing infection-related mortality. Selective digestive decontamination is also used for the prevention of gut-derived infections in acute...

The author draws attention to rare tumours of the digestive tract, their symptoms, treatment and prognosis.

The purpose of this study is to describe the histological and histochemical features of digestive tract intwo aquarium fishes with different types of feeding habits which are omnivorous (Walking catfish) andcarnivorous (piranha), respectively. Five adult Walking catfish (L: 26.4 ± 3.4 cm, W: 265 ± 55 g) and fiveadult piranha (L: 23.6 ± 4.5 cm, W: 247 ± 50 g) were used for this study. The fishes...

Interactions between bacteria which constitute the microflora of the digestive tract may be antagonistic or synergic. Certain bacteria can form a barrier to prevent colonisation of the gut by bacteria of other species or other strains of the same species. This review of current research refers to experiments on gnotoxenic animals, with mention of Escherichia coli and species of Clostr idium, La...

ACUTE abdominal conditions so frequently cause death, and chronic lead to so long continiued ill-health and, often, dangerous complications, that it is obvious that (liagnosis with a view to treatment should be made as sootn as possible. It is essential that the diagnosis be as certain and exact as may be, for, in the acute case, its accuracy may be a matter of paramount importance, while, in t...