Xu hướng sử dụng vật liệu mặt đường bê tông asphalt tái chế (Reclaimed Asphalt Pavement - RAP) để sản xuất đang ngày càng trở nên phổ biến ở trên thế giới vì những lợi ích mang lại về kỹ thuật, kinh tế và môi trường. Tuy nhiên, khi hàm lượng RAP cao được có thể gây ra ảnh hưởng tiêu cực đến các tính năng của hỗn hợp. Do vậy, phụ gia sinh thường cải thiện chất bitum hợp chế. Bài báo trình bày ng...

In previous work we have presented a class of algebras enhanced with two contact relation used in spatial reasoning on the basis of rough sets. In this paper we present a relational logic for such structures in the spirit of Rasiowa – Sikorki proof systems. ⇤Ivo Düntsch gratefully acknowledges support by the Natural Sciences and Engineering Research Council of Canada Discovery Grant 250153. †Ew...

Although tightly linked, the TCR alpha and delta genes are expressed specifically in T lymphocytes, whereas the Dad1 gene is ubiquitously expressed. Between TCR alpha and Dad1 are eight DNase I hypersensitive sites (HS). HS1 colocalizes with the TCR alpha enhancer (Ealpha) and is T cell-specific; HS2, -3, -4, -5, and -6 map downstream of HS1 and are tissue-nonspecific. The region spanning HS2-6...

The vav gene is expressed in all hematopoietic but few other cell types. To explore its unusual compartment-wide regulation, we cloned the murine gene, sequenced its promoter region, identified DNase I hypersensitive (HS) sites in the chromatin, and tested their promoter activity with a beta-galactosidase (beta-gal) reporter gene in cell lines and transgenic mice. Whereas fibroblasts had no HS ...

The Kit (White) gene encodes the transmembrane receptor of stem cell factor/Kit ligand (KL) and is essential for the normal development/maintenance of pluripotent primordial germ cells (PGCs), hematopoietic stem cells (HSCs), melanoblasts, and some of their descendants. The molecular basis for the transcriptional regulation of Kit during development of these important cell types is unknown. We ...

Cortactin, an actin binding protein and Lyn substrate, is up-regulated in several cancers and its level is associated with increased cell migration, metastasis and poor prognosis. The identification that the Src kinase Lyn and its substrate HS1 are over-expressed in B-cell chronic lymphocytic leukemia and involved in resistance to chemotherapy and poor prognosis, prompted us to investigate the ...

We report two episodes of recurrent candidemia caused by echinocandin-resistant Candida glabrata in a 69-year-old patient who underwent repeated abdominal surgery. In the first episode of candidemia, an echinocandin-susceptible Candida glabrata strain was isolated, and the patient was treated with caspofungin. The isolates from the later episodes showed resistance to echinocandins. Analysis of ...

The northern Bay of Biscay has previously proven its great potential for recording the ‘Fleuve Manche’ paleoriver (i.e., largest Pleistocene river in Europe) fluvio-glacial activity. In this study, new dinoflagellate cyst (dinocyst) analyses have been carried out at sub-centennial resolution core MD13–3438 to reconstruct deglacial history runoff coupled with European Ice Sheets (EIS) fluctuatio...