OBJECTIVES To demonstrate that small intestinal mucosal ischemia occurs during cardiopulmonary bypass by measuring serum diamine oxidase activity, an index of small intestinal mucosal ischemia, in perioerative patients undergoing cardiovascular surgery with and without cardiopulmonary bypass. METHODS Twelve successive patients who underwent coronary artery bypass grafting with cardiopulmonary...

One factor that is critical to the potential effectiveness of radioimmunotherapy is the design of radiometal-chelated antibodies that will be stable in vivo. Stability in vivo depends on the condition that both the chelate linkage and radiolabeling procedures not alter antibody specificity and biodistribution. In addition, synthesis and selection of the chelating agent is critical for each radi...

(1R,2R-Diaminocyclohexane)oxalatoplatinum(II) (oxaliplatin) is a third-generation platinum anticancer compound that produces the same type of inter- and intrastrand DNA cross-links as cisplatin. In combination with 5-fluorouracil, oxaliplatin has been recently approved in Europe, Asia, and Latin America for the treatment of metastatic colorectal cancer. We present here the crystal structure of ...

in this investigation, attempts were directed to study the inhibitive effects of nitrite and phosphate base inhibitors for the carbon steel alloy samples, which are used in an acid gas treatment process (the sulfiran® solution), in fe-edta solution. electrochemical techniques, i.e. polarization curves and electrochemical impedance spectroscopy (eis), were used to evaluate the inhibition efficie...

Diamine oxidase was prepared from pea (Pisum sativum) seedlings by a new purification procedure involving two h.p.l.c. steps. We studied the optical and electrochemical properties of the homogeneous enzyme and also analysed the hydrolysed protein by several methods. The data presented here suggest that the carbonyl cofactor of diamine oxidase is firmly bound pyrroloquinoline quinone.

Diamine oxidase (histaminase), an enzyme that oxidatively deaminates putrescine and histamine, was purified from human placenta and from pig kidney. Both NH2-terminal sequences are highly homologous to the human kidney amiloride-binding protein, previously thought to be a component of the amiloride-sensitive Na+ channel. Monoclonal antibodies raised against the pig kidney amiloride-binding prot...

In order to investigate the effect of humic acid (HA) and nano-calcium chelate on the cut flowers of gerbera cv. Dune, an experiment was performed as a completely randomized design with two factors and three replications in hydroponic conditions. The first factor included humic acid at 4 concentrations of 0 (control), 500, 1000, and 2000 mg L-1 as drench and the second factor was ass...

We have developed a rapid and reliable bacteriophage quantification method based on measurement of phage single-stranded DNA (ssDNA) using switchable lanthanide chelate complementation probes. One oligonucleotide probe contains a non-fluorescent lanthanide ion carrier chelate and another probe is labeled with a light absorbing antenna ligand. Hybridization of the non-fluorescent complementation...

The carbene-C ,N chelate tetracarbonyl tungsten complex [(CO)4/ W C(Ph)NHC5H4N /-o ] (4), obtained from [(CO)5W / C(Ph)OMe] (3) and o -aminopyridine, reacts with iodine by oxidative decarbonylation to give a single isomer of the carbene-C ,N chelate tricarbonyl dihalogeno tungsten(II) complex [(CO)3I2/ W C(Ph)NHC5H4N /-o ] (5). The analogous reaction of 4 with bromine affords two interconvertin...