BACKGROUND Increased intracranial pressure (ICP) worsens the outcome of acute liver failure (ALF). This study investigates the underlying pathophysiological mechanisms and evaluates the therapeutic effect of albumin dialysis in ALF with use of the Molecular Adsorbents Recirculating System without hemofiltration/dialysis (modified, M-MARS). METHODS Pigs were randomized into three groups: sham,...

overhydrated patients. This made it possible to relieve the uraemic patient from congestive heart failure and to control arterial blood pressure. Ultrafi ltration is generally applied continuously or intermittently, while the dialysis procedure (diffusion of substances across the dialysis membrane) is going on. During the last few years, short-time dialysis (3–4 hr 3 times a week or every other...

Plasma renin activity, fluid and electrolyte balance, and hemodynamic conditions were measured in seven hypertensive patients with end-stage renal disease before and after five exchanges of peritoneal dialytic fluids which removed large amounts of water and sodium, sodium but little water, and little water and sodium, respectively. The subjects had normal plasma renin activity, severe anemia, h...

The catastrophic 2005 hurricane season alerted Americans to the need for a more effective response to mass casualty incidents. To address the needs of the nephrology community, the Kidney Community Emergency Response Coalition (KCERC) was formed, with representatives from more than 50 governmental agencies and private organizations. After completing phase 1 of its work, the KCERC issued recomme...

Abstract Background and Aims There is a clear relationship between volume overload morbidity mortality in hemodialysis patients, which makes it essential to accurately adjust the normohydrated weight. For this, bioimpedance has become an indispensable tool dialysis units. In recent years there been rapid development of lung ultrasound for evaluation pulmonary congestion through quantification B...

AIM Haemodynamic stability of patients during haemodialysis (HD) sessions is of pivotal importance and accurate determination of dry weight remains a challenge. Little information is available about central venous and aortic pressure during dialysis. In this pilot study we used a non-invasive technique to describe the changes in central venous pressure (CVP) during dialysis. METHODS An ultras...

Previs, Stephen F., Richard Fatica, Visvanathan Chandramouli, James C. Alexander, Henri Brunengraber, and Bernard R. Landau. Quantifying rates of protein synthesis in humans by use of H2O: application to patients with end-stage renal disease. Am J Physiol Endocrinol Metab 286: E665–E672, 2004. First published December 23, 2003; 10.1152/ajpendo.00271.2003.—A method is introduced for quantitating...

BACKGROUND Multipass hemodialysis (MPHD) is a recently described dialysis modality, involving the use of small volumes of dialysate which are repetitively recycled. Dialysis regimes of 8 hours for six days a week using this device result in an increased removal of small water soluble solutes and middle molecules compared to standard hemodialysis (SHD). Since protein-bound solutes (PBS) exert im...

In the dialysis clinic, water is an essential vehicle to deliver life-saving treatment to patients suffering from varying degrees of kidney failure, both acute and chronic. Clean water is vital, as the key ingredient used to prepare hemodialysis fluid (dialysate solution), and online generation of substitution fluid for hemodiafiltration. Generally all fluids used to treat patients suffering fr...