This study aims to investigate the clinical efficacy of Dextran 40 plus dexamethasone on the prevention of fat embolism syndrome (FES) in high-risk patients with long bone shaft fractures. According to the different preventive medication, a total of 1837 cases of long bone shaft fracture patients with injury severity score (ISS) > 16 were divided into four groups: dextran plus dexamethasone gro...

The mutant of Pediococcus pentosaceus (SPAm) produced earlier by UV-mutagenesis exhibiting higher dextransucrase activity as compared to wild-type was used. The generated mutant SPAm gave 12.2 mg/ml, a 20% higher dextran than wild-type. Response surface methodology was carried out for further enhancement of dextran production. To enhance dextran production by the mutant SPAm, Plackett-Burman De...

Diffusion exchange of dextran with molecular weights 4.4 and 77 kDa through polyelectrolyte multilayer (PEM) hollow capsules consisting of four bilayers of polystyrene sulfonate/polydiallyldimethylammonium chloride has been investigated using two-dimensional nuclear-magnetic-resonance methods: diffusion-diffusion exchange spectroscopy (DEXSY) and diffusion-relaxation correlation spectroscopy (D...

To clarify the action of dextran sulphate, a heparin analogue, in the clotting of fibrinogen by thrombin, determinations were carried out on the clotting activity, the release of fibrinopeptides from fibrinogen, and the hydrolytic activity of thrombin against a peptide chromogenic substrate in the absence or presence of antithrombin III (heparin cofactor). It was shown that dextran sulphate its...

ABSTFACT Prostaglandin E (PGE1) sensitive adenylate cyclase rEC.4.6.1.1 ATP-pyrophosphaie lyase (cyclizing)] in human platelet lysates is inhibited by dextran sulfate. Inhibition is dose-dependent at the range of l-10 ug/ml. Maximal inhibition obtained was 85% at 30 ug/ml . At a similar range of concentrations dextran sulfate was found to antagonize the anti-aggregating effect of PGEl on adenos...

The dextran content of both mixed juice and very high pol sugar has shown an increase in recent seasons. Laboratory trials have been used to show that thermally stable dextranase could be used to reduce the dextran concentration in evaporator syrup when high levels of dextran are unavoidable. Dextranase treatment of diffuser juices is unsuitable because of the high temperature, low Brix conditi...

Simultaneous determination of glomerular filtration rate by inulin clearance may be required during studies of the renal excretion of the bacterial polysaccharide, dextran. This involves the estimation of both inulin and dextran in the same plasma and urine samples. Unfortunately, dextran interferes with the analysis of inulin, both by the method of Alving, Flox, Pitesky, and Miller (1) and by ...

BACKGROUND We previously compared the safety profile of three formulations of intravenous iron used during 1998-2000 and found higher rates of adverse drug events (ADEs) associated with the use of higher molecular weight iron dextran and sodium ferric gluconate complex compared with lower molecular weight iron dextran. Since that time, iron sucrose has become widely available and clinicians hav...

Abstract Dextran is an exopolysaccharide produces from bacteria that have been shown to be useful in the pharmaceutical and food industries. The goal of this study was screen capable producing dextran Thai fermented foods then maximize production. maximal amount produced by Lactobacillus fermentum OR1 isolated pickled mango juice 65 g/L after 20 h incubation at 30°C 200 rpm DMB2 Medium containi...

The hydrogel synthesized from biocompatible polyaspartamide, and oxidized dextran had stronger adhesion properties when tested on porcine skin than the commercially available fibrin glue.