conclusions clinically, these results are logical because the required dose of alkaloids for treatment of diarrhea is lesser than the needed doses to treat addiction, arthralgia, and paralysis. results the first itm method reduced the strychnine level from 1.083 to 0.577 and brucine from 0.739 to 0.361. for the second and third itm methods, the levels of strychnine reached 0.838 and 0.812, and ...

the toxicity of chlorpyrifos to three iranian populations of two-spotted spider mite, collected from isfahan (isr), yazd (yz) and guilan (gus2) provinces were surveyed using the residual contact vial bioassay. the bioassay results showed that resistance ratios of isr and yz populations were 176.90 and 9.78 fold compared to the gus2 population, respectively. determination of esterase and glutath...

the enzyme rhodanese (thiosulfate: cyanide sulfurtransferase) is a ubiquitous enzyme and its activity ispresent in all living organisms. many functions including cyanide detoxification, formation of iron-sulfurcenters and participation in energy metabolism have been attributed to this enzyme. the enzyme catalyzesthe transfer of a sulfur atom from sulfane containing compounds (such as thiosulfat...

BACKGROUND Aconitum is an indispensable entity of the traditional medicine therapy in Ayurveda and Traditional Chinese medicine (TCM), in spite of its known fatal toxicity characteristics. The prolonged use of this drug, irrespective of its known lethal effects, is governed by the practice of effective detoxification processes that have been used for decades. However, the processing methods of ...

AIMS Home detoxification is a recognized method of treating problem drinkers within their own home environment. The aim of this research is to determine whether a relatively brief psychological intervention adds to its effectiveness. METHODS A pragmatic trial with 91 participants randomly assigned to either the psychological intervention or treatment as usual. Community Psychiatric Nurses wer...

Slow downtitration as a methadone discontinuation method is time-consuming and associated to high dropout rates. Whereas ultra-rapid opiate detoxification methods have recently gained some popularity, they are expensive and may be associated with particular problems in methadone patients. ln the present study, a 3-day detoxification procedure accelerated with a unique dose of naltrexone was use...

Atractyloside (ATR) is a diterpenoid glycoside and occurs naturally in Asteraceae plants, many of which are used in foods and ethnomedicines. The toxicity of ATR has caused fatal renal proximal tubule necrosis and/or centrilobular hepatic necrosis in man and farm animals. A GC/MS screening method was optimized to detect the presence of ATR in Atractylodes species which are important herbs used ...

Most herbivores eat more and survive better when they have access to a variety of foods. One explanation involves the detoxification of plant secondary metabolites (PSMs). By feeding from a variety of plants that contain different classes of PSMs, animals can use multiple detoxification pathways and presumably consume more food. Although popular, this theory is difficult to test because it requ...

Methylated forms of arsenic (As), monomethylarsenate (MMA), and dimethylarsenate (DMA) have historically been used as herbicides and pesticides. Because of their large application to agriculture fields and the toxicity of MMA and DMA, the persistency of these compounds in the environment is of great concern. MMA and DMA sorption and desorption were investigated in soils, varying in mineralogica...