Abstract Chromosomal abnormalities play an important role in classification and prognostication of myelodysplastic syndrome (MDS) patients. However, more than 50% low-risk MDS patients harbor a normal karyotype. Recently, multiplex ligation-dependent probe amplification (MLPA) has emerged as effective robust method for the detection cytogenetic aberrations To characterize subset with karyotype ...

Control of the global epidemic tuberculosis is severely hampered by the emergence of drug-resistant Mycobacterium tuberculosis strains. Molecular methods offer a more rapid means of characterizing resistant strains than phenotypic drug susceptibility testing. We have developed a molecular method for detection of rifampicin-resistant M. tuberculosis based on padlock probes and magnetic nanobeads...

The polarization-related properties of stimulated Brillouin scattering (SBS) processes in long, randomly birefringent, standard optical fibers are examined. Evolution equations for the pump and signal waves, in the presence of both birefringence and SBS, are provided in Jones and Stokes spaces. It is shown that in the undepleted pump regime, the amplification of the SBS signal wave is equivalen...