Background: Serum lipids abnormalities have been observed in various forms of cancers including acute leukemia. Investigators report decreased total cholesterol and HDL, and elevated triglyceride in leukemic patients. Limited studies had been performed to discover the correlation between abnormal lipids profile and disease activity in leukemic patients in Iran. This study was done to evaluate t...

low density lipoprotein (ldl) subclass pattern b is characterized by predominance of small dense ldl. subjects with pattern b tend to have higher triglyceride (tg) and lower levels of high density lipoprotein cholesterol (hdl-c). small dense ldl is associated with increased risk of coronary disease. in this study, effect of non-insulin dependent diabetes mellitus (niddm) on ldl size, plasma tg ...

In four of eleven patients with histologically-proven sarcoidosis (stage II or III), type II-b hyperlipoproteinaemia (HLP) with increased levels of total cholesterol, triglycerides and low density lipoprotein, and a decreased level of high density lipoprotein was observed. These results suggest that type II-b HLP may be associated with sarcoidosis with systemic sarcoid infiltration (stage II or...

background: metabolic syndrome (mets) is a prevalent disorder in pediatric age groups, described by a combination of genetic and environmental factors. sterol regulatory element‑binding transcription factor 1 (srebf‑1) induces the expression of a family of genes involved in fatty acid synthesis. moreover, dysregulation of mir‑33b, which is located within the intron 17 of the srebf‑1 gene, disru...

objectives: turnip leaf has been used in folk medicine of iran for the treatment of diabetes. however,so far no scientific study has been done to support its use in traditional medicine. the present study was carried out to evaluate the possible hypoglycemic efficacy of aqueous extract of turnip leaf (aetl) in diabetic rats. materials and methods: alloxan-induced diabetic rats were orally treat...

In this study, the effect of lovastatin and fluvastatin was compared with placebo in patients with high levels of total cholesterol and low density lipoprotein cholesterol (LDL-C) on the plasma lipid profile. In a prospective single blind clinical trial with convenient sampling, 120 hypercholesterolemic men and women with Tcholesterol ≥220 mg/dL, LDL-C ≥ 160 mg/dL, and triglyceride ≤ 350 mg...

The relationship between the concentrations of intermediate-density lipoprotein (IDL) and other lipoproteins and the extent of coronary artery disease (CAD) was studied in 182 consecutive patients evaluated by selective coronary cineangiography. On univariate analysis, the extent of CAD correlated significantly and positively with very low density lipoprotein (VLDL) cholesterol, IDL cholesterol...

BACKGROUND AND OBJECTIVES To investigate age-specific and sex-specific distributions of blood cholesterol in the general Korean population. SUBJECTS AND METHODS We analyzed data for 8284 men and 9246 women aged ≥10 years who participated in the fifth (2010-2012) Korea National Health and Nutrition Examination Survey. Age-specific means, medians, and selected percentiles were calculated for me...

An increased dietary load of cholesterol (ch) and saturated fat increases serum low density lipoprotein ch (LDL-ch) levels. GH therapy in GH-deficient adults decreases serum LDL-ch levels. In the rat, GH is important for resistance to dietary cholesterol in terms of serum cholesterol levels. The aim of this study was to investigate the influence of GH on the effects of an increase in the intake...