The proteasome is one of the major degradation machineries in eukaryotic cells. It terminates the existence of thousands of short-lived, damaged, misfolded or otherwise obsolete proteins and plays pivotal roles in protein quality control and other vital processes in the cell. However, very little has been known about the mechanisms that control and execute the destruction of the proteasome itse...

Multispectral imaging was employed to collect data on the degradation of an 18 century parchment by a series of physical and chemical treatments. Each sample was photographed before and after treatment by a monochrome digital camera with 21 narrow-band filters, with the objective of assessing algorithms for recovery of text from the images. A template-matching technique was used to detect the c...

JENNIFER KATE WILLIAMS The degradation of soil quality due to anthropogenic causes is globally important, both in terms of ecosystem services and ecological biodiversity. Soil quality reduction is stated to be detrimental for population densities and species diversity of soil invertebrates, including the mesofauna (Acari and Collembola). Within the soil food web, mesofauna occupy several trophi...

A Novel Degraded Video Enhancement N.Chandra Sekhar, V.Purandhar Reddy PG Student SVCE, Tirupati, India. Associate Professor, SVCE, Tirupati ,India. _________________________________________________________________________ ABSTRACT: We show an illustration based way to deal with general upgrade of degraded video frames. The technique depends on building a lexicon with non-debased parts of the V...

heart failure is common in patients with chronic renal disease, either as a complication of renal failure or from shared risk factors, or is the major cause of death in patients on dialysis. at present, end stage renal disease (esrd) patients who have systolic heart failure are considered high-risk for surgery; and nephrologists and cardiologists are reluctant to refer these patients for kidney...

MAD2 inhibits the anaphase-promoting complex when chromosomes are unattached to the mitotic spindle. It acts as a tumor suppressor gene because MAD2+/-cells enter anaphase early and display chromosome instability, leading to the formation of lung tumors in mice. Complete MAD2 inactivation has not been identified in human tumors, although partial defects are prevalent. By employing RNA interfere...

Models of sepsis have been instructive in understanding the sequence of events in animals and, to an extent, in humans with sepsis. Events developing early in sepsis suggest that a hyperinflammatory state exists, accompanied by a buildup of oxidants in tissues reflective of a redox imbalance. Development of immunosuppression and degraded innate and adaptive immune responses are well-established...

assessment of diversity and species richness in the understanding of ecosystem functions, protect and preserve genetic resources, evaluation and control of environmental change and the success or failure will help natural resource management programs. arbitrary banning livestock grazing program and one of the most common and perhaps the most degraded pastures and reduced the diversity and speci...

We advance a knowledge-based learning method that augments conventional generalization to permit concept acquisition in failure domains. These are domains in which learning must proceed exclusively with failure examples that are relatively uninformative for conventional methods. A domain theory is used to explain and then systematically perturb the observed failures so that they can be treated ...

Static risk analysis techniques (SRATs) use event graphs and assessment models. Those are not time-based hence inadequate to model dynamic stochastic systems. This paper proposes a novel approach such systems using Dynamic Fault Trees (DFT). The proposed is called Generic Agent-Based Model (GDABM) for analysis. GDABM built on top of the well-known Modeling Simulation (ABMS) technique. can syste...