Infectious diseases are responsible for thousands of worldwide early death .Many commercial antibiotics have been used to control human's infectious diseases all over the world. Calotropis procera Linn a wild growing plant of Asclepiadaecae family is known to possess multifarious medicinal properties. Total 80 non repetitive clinical E. coli strains recovered during 7 month, a...

Chemical investigation of the 50% ethanol eluate fraction from a macroporous resin of flowers of Datura metel L. collected in the Jiangsu Province of China resulted in the isolation of two new withanolides, baimantuoluoline G (1) and baimantuoluoside H (2). Their structures were elucidated as (12β,6β,22R)-1,10-seco-6,12,27-trihydroxy-26-oxo-witha-3,5,24-trienolide-1-oic acid-ε-lactone (1) and (...

Cell-suspension cultures of Capsicum annuum L., Solanum aculeatissimum Jacq. and, Datura fastuosa L. (Solanaceae) were established and investigated for the ability to biotransform exogenously-supplied hydroquinone to arbutin. All cultures exhibited good 24-day growth in Murashige and Skoog medium, supplemented with 2,4-dichlorophenoxyacetic acid and benzylaminopurine as plant growth regulators,...

Pharmacognosy Research,2022,14,2,146-152.DOI:10.5530/pres.14.2.21Published:April 2022Type:Original ArticleAuthors:Shakila Ramachandran, Saravanan Meenatchisundaram, Subashini Subramanian, Sujith Thatipelli, Achintya Kumar Mandal, and Rajesh Allu Author(s) affiliations:Shakila Ramachandran1,*, Meenatchisundaram2, Subramanian3, Thatipelli4, Mandal5, Allu6 Department of Chemistry, Siddha Central R...

A new withanolide, named withawrightolide (1), and four known withanolides (2-5) were isolated from the aerial parts of Datura wrightii. The structure of compound 1 was elucidated through 2D NMR and other spectroscopic techniques. In addition, the structure of withametelin L (2) was confirmed by X-ray crystallographic analysis. Using MTS viability assays, withanolides 1-5 showed antiproliferati...

Four new withanolides named dmetelins A-D (compounds 1-4), along with the known compound 7α,27-dihydroxy-1-oxo-witha-2,5,24-trienolide (5) were isolated from the leaves of Datura metel L. (Solanaceae). Their structures were elucidated on the basis of detailed analysis of 1D and 2D NMR and mass spectrometry data. All the compounds were evaluated for their inhibitory effects on lipopolysaccharide...

O artigo consiste no estudo florístico das Apocynaceae s.l. restingas paraenses. São apresentadas descrições, ilustrações e chaves dicotômicas espécies, bem como informações sobre distribuição geográfica, comentários taxonômicos fenologia. As do estado Pará estão representadas por 12 distribuídas em 11 gêneros. gênero mais representativo foi Mandevilla Lindl., com duas espécies. Calotropis proc...