This research was designed to study sexual differences in place conditioning induced by morphine in offspring born of female Wistar rats mated with drug-naïve males. Mothers were exposed to morphine during the 14th-16th days of gestational. Control dams were simply saline-injected. Female and male virgin offspring born of morphine-treated or saline-treated mothers were separately housed until b...

the purpose of the present study was to determine the role of medial prefrontal cortex (mpfc) dopaminergic system in fear conditioning response considering individual differences. animals were initially counterbalanced and classified based on open field test, and then were given a single infusion of the dopamine agonist, amphetamine (amph) and antagonist, clozapine (clz) into the medial prefron...

Abstract Surface-based modelling provides a computationally efficient approach for generating geometrically realistic representations of heterogeneity in reservoir models. However, conditioning Surface-Based Geological Models (SBGMs) to well data can be challenging because it is an ill-posed inverse problem with spatially distributed parameters. To aid fast and conditioning, we use here SBGMs t...