By combining the partition method for enrichment of sulfatides without any chromatographic procedures and the preparation method of lysosulfatides, we succeeded in analyzing these sulfated glycosphingolipids from biological materials by matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) to reduce the complexity of mass fragmentation patterns within a...

PURPOSE Carbamazepine is a poor water soluble drug and its bioavailability is limited by dissolution rate. Dissolution, serum concentration and anticonvulsive effect of the drug have been evaluated after cogrinding with microcrystalline cellulose. A cogrinding technique was used to increase the dissolution, serum concentrations and anticonvulsive effect of the drug. A novel deconvolution techni...

PURPOSE Novel therapeutic strategies are needed to prevent the tumor recurrence or metastasis after liver transplantation for hepatocellular carcinoma (HCC). This study was to investigate the effect of rapamycin, alone and in combination with sorafenib, on HCC in vivo. EXPERIMENTAL DESIGN Xenograft of a highly metastatic human HCC tumor (LCI-D20) was used to evaluate primary tumor growth and ...

The complementary relationship (CR) of evapotranspiration allows the estimation of the actual evapotranspiration rate (ETa) of the land surface using only routine meteorological data, which is of great importance in the Tibetan Plateau (TP) due to its sparse observation network. With the highest in situ automatic climate observation system in a typical semiarid alpine steppe region of the TP, t...

PURPOSE To demonstrate the feasibility of using a knowledge base of prior treatment plans to generate new prostate intensity modulated radiation therapy (IMRT) plans. Each new case would be matched against others in the knowledge base. Once the best match is identified, that clinically approved plan is used to generate the new plan. METHODS A database of 100 prostate IMRT treatment plans was ...

Saturated hydraulic conductivity is one of the most essential soil parameters, influencing surface runoff and water erosion formation. Both field laboratory methods measurement this property are time or cost-consuming. On other hand, empirical very easy, quick costless. The aim work was to compare 15 pedotransfer models determination their usefulness for assessment saturated highly eroded loess...

The paper presents the results of studies to determine suitability dump battle fired ceramic products based on kaolin clays Angren deposit, positive effect addition fractionated formation structure and physico-mechanical properties portland cement stone is established. For use as an additive in cement, need for fractionation production waste with separation burnt part was noted; its chemical mi...

Silkworms are one type of live food that has begun to be intensified in their cultivation activities Indonesia. This study aimed determine the effect feeding/dried substrate different doses on growth performance silkworms. The second aim was appropriate dose dry for silkworm cultivation. used a completely randomized design (CRD) with 4 treatments media at 114 g/m2 (D10), 228 (D20), and 324 (D30...