Phytochemical Screening, Antibacterial and Cytotoxic Activities of Petroselinum crispum Leaves Grown in Oman.Petroselinum crispum belongs to the Apiaceae family, is a well-known spice and vegetable. The essential oil obtained from the fruit has also strong action on the central nervous system. Present study is designed to evaluate the phytochemical screening, antibacterial and cytotoxic ac...

Quinazolinones are a group of fused heterocyclic compounds which have valuable biological properties including cytotoxic, antibacterial and antifungal activities. Thiazole group-containing compounds have been also reported to have a wide range of biological activities such as antitumor, anti-inflammatory, analgesic and antibacterial effects. Due to valuable cytotoxic effects of both thiazole gr...

A series of 1,4-disubstituted-3,4-dihydroisoquinoline derivatives designed as tubulin polymerization inhibitors were synthesized. Their cytotoxic activities against the CEM leukemia cell line were evaluated. Most of them displayed moderate cytotoxic activities, and compounds 21 and 32 showed good activities with IC50 of 4.10 and 0.64 μM, respectively. The most potent compound 32 was further con...

Ferula communis L., subsp. communis, namely giant fennel, has extensively been used in traditional medicine for a wide range of ailments. Fresh plant materials, crude extracts and isolated components of F. communis showed a wide spectrum of in vitro and in vivo pharmacological properties including antidiabetic, antimicrobial, antiproliferative, and cytotoxic activities. The present paper, revie...

chromanone derivatives demonstrate remarkable cytotoxity against a varieties of cancer cell lines. novel 9-[hydroxy(substitutedphenyl)methyl]-2,2-dimethyl-2,3,8,9- tetrahydro-4h,10h-pyrano[2,3-f]chromene-4,10-diones as glyasperin analogues were synthesized in four steps from known 4-chromone 1. the key step was the preparation of chromane dione 5a by regioselective intramolecular cyclization re...

Quinazolinones are a group of heterocyclic compounds that have important biological activities such as cytotoxicity, anti-bacterial, and anti-fungal effects. Thiazole-containing compounds have also many biological effects including antitumor, antibacterial, anti-inflammatory, and analgesic activities. Due to significant cytotoxic effects of both quinazoline and thiazole derivatives, in this wor...

phytochemical screening, antibacterial and cytotoxic activities of petroselinum crispum leaves grown in oman.petroselinum crispum belongs to the apiaceae family, is a well-known spice and vegetable. the essential oil obtained from the fruit has also strong action on the central nervous system. present study is designed to evaluate the phytochemical screening, antibacterial and cytotoxic activit...

In this study, the enzyme activity of anthraquinone compounds which were synthesized beforehand by our research group was investigated. Molecular docking studies performed for 1-(4-aminophenylthio)anthracene-9,10-dione (3) and 1-(4-chlorophenylthio)anthracene-9,10-dione (5). Compound 3 from reaction 1-chloroanthraquinone (1) 4-aminothiophenol (2). 5 4-chlorothiophenol (4). Anthraquinone analogs...

Synthesis of Silver Nanoparticles using Methanol Extract Bunium Persicum and the Evaluation its Cytotoxic, Antileishmanial, Antimicrobial Activities