Cytomegalovirus (CMV) reactivation after allogeneic hematopoietic stem cell transplant (allo-HSCT) is mainly due to an increase of latent viremia in previously exposed patients. Furthermore, CMV this setting has a significant impact on patient survival. Traditional approach post allo-HSCT was pre-emptive treatment with antivirals the case increased viremia. However, since 2017, new antiviral co...

Cytomegalovirus (CMV) is the most common opportunistic pathogen affecting renal transplant recipients, especially in first months. CMV-seropositive recipients (CMV R+) are at intermediate risk for CMV disease, but this enhanced among R+ receiving T-cell depleting induction, compared to non-depleting induction. In second group, data favor of prophylactic antiviral treatment with valganciclovir r...

Little is known about cytomegalovirus (CMV) infection after face transplantation, since only two of the 11 cases of face transplantation reported worldwide have documented a CMV infection after transplantation. Herein, we present the first report of a composite-tissue face allotransplant recipient at high risk for CMV infection (D(+)/R(-) [CMV serpositive donor positive/CMV seronegative recepto...

PURPOSE This study aims to report a novel finding of posterior subhyaloid precipitates (PSPs) in two patients with cytomegalovirus (CMV) retinitis. METHODS A small case series was conducted. RESULTS Clinical findings, treatment, and follow-up of two patients with CMV and PSPs are presented. CONCLUSIONS Inflammatory precipitates may collect in the posterior subhyaloid space in acute CMV re...

Gastrointestinal infection with cytomegalovirus (CMV) is usually found in immunocompromised patients and rarely affects immunocompetent subjects. We describe two immunocompetent patients who had primary CMV infection, and in both the disease was associated with ulcerative colitis. Both patients recovered from the CMV infection spontaneously.

I NTESTINAL transplantation (ITx) is now feasible with actuarial patient and graft survivals at 24 months exceeding 74% and 59%, respectively.l The occurrence of opportunistic infections such as cytomegalovirus (CMV), however, has significantly hindered further improvement in long term outcome. In this study, we focus upon our experience with CMV after ITx in children and analyze the influence ...

Emerging evidence demonstrate a high prevalence of cytomegalovirus (CMV) proteins and nucleic acids in different tumors. CMV is confined to tumor cells and non-cancer cells in close proximity to tumors are consistently virus negative. CMV confers both oncogenic and oncomodulatory mechanisms, and may therefore provide a novel target in cancer treatment.

Cytomegalovirus (CMV) remains one of the most common infections after solid organ transplantation, resulting in significant morbidity, graft loss, and occasional mortality. Management of CMV varies considerably among transplant centers. A panel of experts on CMV and solid organ transplant was convened by The Infectious Diseases Section of The Transplantation Society to develop evidence and expe...

UNLABELLED Data on cytomegalovirus infection (CMV) prevalence and course in hospitalized infants are rather scarce, obsolete and considerably inconsistent. AIM to determine the prevalence, rate of clinical manifestations, risk factors and predictive capacity of clinical manifestations of CMV infection in hospitalized infants during their first year of life. PATIENTS AND METHODS All 163 infa...

Hyperimmune globulins were reported to prevent and treat fetal cytomegalovirus (CMV) infection during pregnancy. Here, we report that infusions of standard human intravenous immunoglobulin significantly increase CMV IgG titers and avidity indexes in pregnant women, paving the way to their use for passive transfer of maternal CMV humoral immunity to fetuses. Preliminary data on perinatal outcome...