Infectious bursal disease (IBD) is an economically important viral disease of chickens with worldwide distribution which suppresses the immune system of young chickens. VP2 is the major host-protective protein of infectious bursal disease virus (IBDV). The encoding region of VP2 protein was PCR amplified from a plasmid containing a cDNA fragment of large genomic segment of IBDV, strain D78. Thi...

Submit Manuscript | http://medcraveonline.com Abbreviations: SPR: Surface plasmon resonance; ISFET: Ion Sensitive Field Effect Transistor; EnFET: Enzyme Field Effect Transistor; μTAS: Micro Total Analysis System; HCMV: Human Cytomegalovirus; ELISA: Enzyme-Linked Immunosorbent Assay; CNC: Computer Numerical Control; CAD: Computer Assisted Design; BSA: Bovine Serum Albumin; HPAb: Human Polyclonal...

Two infants were considered to have acquired cytomegalovirus (CMV) infection from blood transfusions screened for the presence of CMV antibody by a haemagglutination assay. Further samples from the same donors were tested by a latex agglutination test; six of 18 (33%) previously believed seronegative were found to be seropositive.

Five hundred blood donors were evaluated for cytomegalovirus (CMV) viruria, antibody to CMV early antigens (EA-ab), CMV seropositivity by two screening assays, and CMV-specific immunoglobulin M by two methods. Three donors were viruric, EA-ab positive, and seropositive; two viruric donors were immunoglobulin M positive.

Utilizing a human cytomegalovirus-specific fusion inhibitor and an antiglycoprotein H antibody, we studied the role of virion fusion in interferon-stimulated gene (ISG) induction. Our results indicate that ISG induction does not occur when virion-mediated, post-high-affinity attachment events are inhibited by either reagent. Thus, virion-mediated postattachment events, such as fusion, are requi...

Key words: fibrosing cholestatic hepatitis; graft failure; surface antigen, as well as anti-HBc and anti-HBe hepatitis B virus; interferon-a; renal transplantation antibodies. He was seronegative for HBeAg, anti-HCV antibody (ELISA 2) and cytomegalovirus (CMV). Serum hepatitis B virus DNA determined by PCR was negative. His pretransplant liver function was normal.