Extrahepatic biliary stenosis can be caused by benign and malignant disorders. In most cases, a tissue diagnosis is needed for optimal management of patients, but the sensitivity of biliary cytology for the diagnosis of a malignancy is relatively low. The additional diagnostic value of K-ras mutational analysis of endobiliary brush cytology was assessed. Endobiliary brush cytology specimens obt...

BACKGROUND Human papillomavirus (HPV)-based screening needs triage. In most randomized controlled trials (RCTs) on HPV testing with cytological triage, cytology interpretation has been blind to HPV status. METHODS Women age 25 to 60 years enrolled in the New Technology in Cervical Cancer (NTCC) RCT comparing HPV testing with cytology were referred to colposcopy if HPV positive and, if no cerv...

Abstract Background To evaluate the clinical effectiveness of a novel CellDetect staining technique, compared with fluorescent in situ hybridization (FISH), and urine cytology, diagnosis urothelial carcinoma (UC). Methods A total 264 patients suspicious UC were enrolled this study. All tissue specimens collected by biopsy or surgery. Urine specimen was obtained for examinations prior to surgica...

Aim: Fine-needle aspiration cytology (FNAC) in the preoperative diagnosis of salivary gland (SG) masses is a very fast, inexpensive, and reliable diagnostic method. In our study, correlation cytological-histopathological cases diagnosed with fine needle clinic was investigated, possible causes entrapment discordant were discussed. Material Methods: Salivary FNAC histopathological between 2008 2...

BACKGROUND We recently reported, using a receiver operating characteristic area metric, the first meta-analytic comparison of the relative accuracy of cervical and anal cytology in detecting moderate or severe histopathologic lesions by magnification directed punch biopsy. The aim of the present research was to meta-analytically examine cut-point specific operating characteristics (sensitivity,...

The International Federation of Gynecology and Obstetrics (FIGO) changed the surgical staging criteria for endometrial cancer in 2009, namely combining FIGO 1988 Stage IA and IB in FIGO 2009 Stage IA, eliminating cervical glandular involvement from Stage II, and removing peritoneal cytology as criteria from Stage IIIA (3). This review of the literature sheds light on the continued debate among ...

BACKGROUND Epidermal growth factor receptor (EGFR) mutation is predictive for the efficacy of EGFR tyrosine kinase inhibitors in advanced non-small-cell lung cancer (NSCLC) treatment. We evaluated the performance, sensitivity, and concordance between five EGFR tests. MATERIALS AND METHODS DNA admixtures (n = 34; 1%-50% mutant plasmid DNA) and samples from NSCLC patients [116 formalin-fixed pa...

Cervical cancer is a serious disease that threatens the health of women worldwide. This study compared the sensitivities and false-positive rates of cervical cytology (Pap smear), human papilloma virus (HPV) DNA test, cervicography, first double-combined testing (cervical cytology and HPV DNA test), second double-combined testing (cervical cytology and cervicography) and triple-combined testing...

BACKGROUND Peritoneal lavage cytology in the staging of pancreatic cancer is not widely used given improvements in computed tomography (CT). The aim of this study was to determine the utility of peritoneal lavage cytology in predicting survival in locally advanced pancreatic cancer. METHODS Between 2000 and 2008, 202 patients with biopsy-proven pancreatic cancer who were determined by pancrea...

Background: Cervical cancer presents as major cause of morbidity and mortality especially in developing countries like India. Various screening programs are implemented for its early detection and treatment, which makes it imperative to have a reliable screening investigation for wider application. Objective : TO evaluate the role of Liquid base cytology and Colposcopy and compare their efficac...