نتایج جستجو برای: cytogenetic effects

تعداد نتایج: 1555618  

Journal: :Experimental oncology 2013
E A Diomina V F Chekhun

AIM On the basis of the cytogenetic research, to develop and validate the strategy of the measures to prevent the stochastic effects of low-doses radiation on humans. METHODS Test system with human peripheral blood lymphocytes, metaphase analysis of chromosomal aberrations was used. Cells were cultured according to the standard procedures with modifications. The analysis of painted chromosome...

Journal: :iranian journal of medical sciences 0
akbar safaei department of pathology, school of medicine, shiraz university of medical sciences, shiraz, iran jahanbanoo shahryari department of pathology, school of medicine, shiraz university of medical sciences, shiraz, iran mohamad reza farzaneh department of pathology, school of medicine, shiraz university of medical sciences, shiraz, iran narjes tabibi department of pathology, school of medicine, shiraz university of medical sciences, shiraz, iran marzieh hosseini department of pathology, school of medicine, shiraz university of medical sciences, shiraz, iran

background: acute lymphoblastic leukemia (all) is the sixth most common malignancy in iran. cytogenetic analysis of leukemic blasts plays an important role in classification and prognosis in all patients. the purpose of this study was to define the frequency of chromosomal abnormalities of all patients in adults and children in fars province, iran. methods: in this cross-sectional study, we eva...

2010
Amr R. Ibrahim Christos Paliompeis Marco Bua Dragana Milojkovic Richard Szydlo Jamshid S. Khorashad Letizia Foroni Alistair Reid Hugues de Lavallade Katayoun Rezvani Francesco Dazzi Jane F. Apperley John M. Goldman David Marin

We analyzed a cohort of 26 patients with chronic myeloid leukemia who had failed imatinib and a second tyrosine kinase inhibitor but were still in first chronic phase and identified prognostic factors for response and outcomes. The achievement of a prior cytogenetic response on imatinib or on second-line therapy were the only independent predictors for the achievement of complete cytogenetic re...

Journal: :Annals of Pathology and Laboratory Medicine 2021

According to the World Health Organization (WHO) 2016 classification, acute promyelocytic leukemia (APL) is placed in category of AML with recurrent cytogenetic abnormalities. Cytogenetic confirmation reciprocal translocation t(15:17) essential criteria for diagnosis this entity. However, these tests may have a significant time delay and it usually characteristic morphology abnormal promyelocyt...

2015
A M Rajan S V Rajkumar

The interpretation of cytogenetic abnormalities in multiple myeloma (MM) is often a challenging task. MM is characterized by several cytogenetic abnormalities that occur at various time points in the disease course. The interpretation of cytogenetic results in MM is complicated by the number and complexity of the abnormalities, the methods used to detect them and the disease stage at which they...

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