UNLABELLED During the menopause, levels of SHBG, IGF-I and IGFBPs are significantly modified by the use of different HRT regimens. OBJECTIVE The aim of this study is to evaluate the influence of three different HRT regimens on serum levels of SHBG, IGF-I, IGFBP-1 and IGFBP-3 in postmenopausal women. METHODS 41 postmenopausal women requesting HRT were enrolled in the study. Subjects were div...

Transgender women are assigned male at birth but identified as women. The incidence of gender dysphoria is estimated to be around 1% the population. Gender may associated with depression and low quality life, which in most cases improves during gender-affirming hormonal treatment (GAHT). Feminizing for transgender or non-binary people typically includes natural estrogen (estradiol). Additional ...