Quaternisation of 3,5-diaryl-1,2,4-thiadiazoles with trimethylsilylmethyl triflate at 40 8C occurred at N-2. Separate desilylation of the salts resulted in a ring expansion to substituted 2H-1,3,5-thiadiazines 5. Heating of these with ethanolic sodium ethoxide caused sulfur extrusion and ring contraction to 2,4-disubstituted imidazoles 6. 3,4-Diaryl1,2,5-thiadiazoles were less reactive to alkyl...

Selective release of inflammatory materials from leukocyte lysosomes is reduced by compounds which increase cyclic 3',5'-adenosine monophosphate (cAMP) levels in suspensions of human leukocytes and is augmented by agents which increase cyclic 3',5'-guanosine monophosphate (cGMP) levels in these cell suspensions. Lysosomal enzymes are released in the absence of phagocytosis when cytochalasin B (...

Introduction Bar extrusion is a process in which a block of metal (billet) is forced to flow by compression through a tool (die) opening of a smaller crosssectional area than that of the original billet. There are two basic types of bar extrusion: direct and indirect. The most important and common method used is the direct extrusion (Lange 1988). Figure 1 shows the principle of direct bar extru...

–The importance of flow through sudden change in flow passages lies in the numerous industrial applications such as, polymer processing, injection molding, biomedical instruments, extrusion, thermoforming etc. In this work, fluid flow through an axi-symmetric sudden contraction flow passages has been carried out using commercial CFD tools. Flow in the inverse direction, which represents flow th...

In this study, five microcrystalline cellulose (MCC) grades were physically characterized and their extrusion-spheronization behaviours were characterized in terms of water requirements and pellet shape profiles. It was found that the MCC grades differed significantly in the physical properties investigated. Physical properties of MCC were found to influence the water requirement for extrusion-...

The ZK61 alloy rods with different grain sizes and crystallographic texture were successfully fabricated by cyclic extrusion and compression (CEC). Their room-temperature tension & compression yield strength displayed a significant dependence on grain size and texture, essentially attributed to {10-12} twinning. The texture variations were characterized by the angle θ between the c-axis of ...

This paper analyzes the effect of thin and thick walls on functional properties 3D printed cell structures, designed from open structures inspired by natural world. Different types unit cells with same density are introduced. The studied in morphology mechanical performance, particular effective density, compressive stiffness, energy absorption under cyclic loading. Material extrusion process t...