A case of acute sarcoidosis associated with the simultaneous appearance of cutaneous leucocytoclastic vasculitis and erythema nodosum is reported. Circulating immune complexes were demonstrated and may have been important in the pathogenesis of both types of skin lesion.

Background: Sarcoidosis is a multisystem, granulomatous & chronic illness which typically affecting lymph nodes lungs also any organ system. We aimed to evaluate the tofacitinib effectiveness as cutaneous pulmonary sarcoidosis steroid-sparing treatment.
 Methods: This retrospective cohort observational research was performed on 45 cases aged from 20 65 years old, both sexes, forced vit...

Sarcoidosis is a chronic, multisystemic disease commonly affecting the lungs and lymphatic system and is characterized by the formation of noncaseating granulomas. Although several reports are available on cases developing both sarcoidosis and cancer metachronously, cases of simultaneous diagnosis of these diseases have rarely been reported. A 67-year-old woman diagnosed with endometrial cancer...

1. Newman LS, Rose CS, Maier LA. Sarcoidosis. N Engl J Med 1997; 336:1224-34. 2. Pietropaoli A, Modrak J, Utell M. Interferon-α therapy associated with the development of sarcoidosis. Chest 1999; 116:569-72. 3. Kikawada M, Ichinose Y, Kunisawa A, et al. Sarcoidosis induced by interferon therapy for chronic myelogenous leukaemia. Respirology 1998; 3:41-4. 4. Hoffman RM, Jung MC, Motz R, et al. S...

Sarcoidosis is a common multisystem granulomatous disease of unknown etiology. Overall the prognosis is not necessarily deleterious because organ involvement is usually asymptomatic except for ocular or cutaneous involvements and the disease is often selflimiting. Cardiac Sarcoidosis is rare (5%) but once the heart is involved, the patient’s prognosis is poor because of the development of fatal...

We present a sixty three year old female with erythematous itching rash over the lower limbs since 4 years, rash over abdomen since 2 years, rash over forehead and scalp since 1 year. She denied any other systemic complaints. Clinically she had pallor and well defined erythematous, hyperpigmented plaques over the shin bilaterally, symmetrical with few depigmented areas over the lower aspect of ...

Sarcoidosis is a systemic disorder of unknown cause that is characterized by the presence of noncaseating granulomas. The radiological findings associated with sarcoidosis have been well described. The findings include symmetric, bilateral hilar and paratracheal lymphadenopathy, with or without concomitant parenchymal abnormalities (multiple small nodules in a peribronchovascular distribution a...

BACKGROUND AND OBJECTIVE Scar sarcoidosis is a circumscribed form of cutaneous sarcoidosis, which is often very difficult to treat. To date, therapeutic approaches have yielded little success and often been accompanied by adverse effects, some of which are severe. Laser treatment is one alternative, which has proven to be effective in a dramatically increasing number of cases over the past year...

Löfgren's syndrome is an acute form of sarcoidosis that mostly presents with erythema nodosum, periarticular ankle inflammation, arthritis, conjunctivitis, and unilateral or bilateral hilar or right paratracheal lymphadenopathy. Erythema nodosum is the most common cutaneous lesion in acute sarcoidosis, but it is histologically nonspecific, as it does not reveal sarcoidal granulomas upon microsc...

A 66-year old woman with chronic HCV hepatitis was being evaluated for antiviral therapy. On admission we observed a reddish indurated cutaneous lesion of about 1.5/2cm affecting the nose. Laboratory tests revealed proteinuria (5g/ 24 hours), mild hepatocytolysis, RNAHCV level of 900,000UI/ml and positive serum cryoglobulins. Biopsy from the cutaneous lesion revealed circumscribed non-caseating...