purpose: to report a case of delayed corneal perforation secondary to topical diclofenac usage after myopic lasek and review of literature. patients and findings: a 25-year-old female with history of myopic lasek 2 months before referred to her surgeon with epithelial defect, stromal thinning and infiltration. she was treated with antimicrobial medications for infectious keratitis for one week....

An investigation into the technical and commercial feasibility of computer-based interactive simulation of the human heart was conducted. An experimental research application was developed and served as a proof of concept for the simulation models during the research phase. The follow-on development phase will be directed towards a pre-production prototype of a virtual heart organ. The prototyp...

The formation and operation of dynamic and open virtual organisations is a central concern in business-to-business e-commerce. Virtual organisations enable partner companies to develop and manufacture customised products with low costs and rapid delivery. Agent-based architectures are an effective platform for such virtual organisations because they provide mechanisms to allow organisations to ...

This article presents the development of a knowledge-based expert system for a non-trivial application domain, i.e. selecting a customised postgraduate study program from existingand targeted sets of skills. Following a customised spiral development paradigm, the paper describes the problem domain, followed by the concepts and requirements involved in the expert system design. The main design c...

The formation and operation of dynamic and open virtual organisations is a central concern in business-to-business e-commerce. Virtual organisations enable partner companies to develop and manufacture customised products with low costs and rapid delivery. Agent-based architectures are an effective platform for such virtual organisations because they provide mechanisms to allow organisations to ...

This paper describes a mechanism for providing hypertext documents that accommodate individual learner’s different needs. The customisation of the text can take account of a variety of factors, including the learner’s background, interests and preferred learning style. Central to the customisation is the user model that represents the learner’s preferences and knowledge. We describe the way tha...