نتایج جستجو برای: current clamp

تعداد نتایج: 792696  

Journal: :Journal of neurophysiology 2013
Mahito Ohkuma Fusao Kawai Ei-ichi Miyachi

Olfactory perception is influenced by behavioral states, presumably via efferent regulation. Using the whole cell version of patch-clamp recording technique, we discovered that acetylcholine, which is released from efferent fibers in the olfactory mucosa, can directly affect the signal encoding in newt olfactory receptor cells (ORCs). Under current-clamp conditions, application of carbachol, an...

2001
V. Axelrad

Electrostatic Discharge (ESD) is generally recognized as an increasingly important issue for modern integrated circuits. Thinner gate oxides, complex chips with multiple power supplies and/or mixed-signal blocks, larger chip capacitance and faster circuit operation all contribute to increased ESD-sensitivity of advanced semiconductor products [1]. Detailed understanding of complex circuit-devic...

Journal: :Journal of neurophysiology 2003
De-Lai Qiu Chun-Ping Chu Tetsuro Shirasaka Takashi Nabekura Takato Kunitake Kazuo Kato Masamitsu Nakazato Takahiko Katoh Hiroshi Kannan

The effect of neuromedin U (NMU) on rat paraventricular nucleus (PVN) neurons was examined using whole cell patch-clamp recordings. Under current-clamp, 31% of PVN parvocellular neurons (n = 243) were depolarized by 100 nM NMU, but magnocellular neurons were not affected. NMU (10 nM to 1 microM) resulted in increased basal firing rate and depolarization in a dose-dependent manner with an EC50 o...

Introduction: Resveratrol (3,5,4-trihydroxystilbene) a non-flavonoid polyphenol found in some plants like grapes, peanuts and pomegranates, possesses a wide range of biological effects. Evidence indicates that resveratrol has beneficial effects on nervous system to induce neuroprotection. However, the cellular mechanisms of the effects are not fully determined. In the present study, the cellula...

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