We study the dynamics of radiation belt electrons during a 10-day quiet period perturbed by substorm activity and preceding high-speed stream (HSS), aiming at global description belts in L-shell, L [2, 6], energy [0.1, 10] MeV. combine Van Allen Probes observations Fokker-Planck numerical simulations pitch-angle diffusion. The model uses event-driven pitch angle diffusion coefficients from whis...

A clinically practical algorithm has been developed for the treatment of liver cancer by the administration of rhenium-188 ((188)Re)-labeled lipiodol via the hepatic artery. This algorithm is based on the "maximum tolerated-activity" paradigm for radionuclide therapy. A small "scout" activity of (188)Re-labeled lipiodol is administered to the patient before the actual therapeutic administration...

OBJECTIVE To estimate stroke risk for diabetes, isolated or associated to metabolic syndrome (MS) according WHO and National Cholesterol Education Program (NCEP) criteria. DESIGN Multicentre and prospective cohort study. SETTING Primary health care. PARTICIPANTS Subjects between 55-85 years-old without any evidence of stroke, included from 1998 in a random population sample for MS follow-...

In cluster detection of disease, the use of local cluster detection tests (CDTs) is current. These methods aim both at locating likely clusters and testing for their statistical significance. New or improved CDTs are regularly proposed to epidemiologists and must be subjected to performance assessment. Because location accuracy has to be considered, performance assessment goes beyond the raw es...

BACKGROUND The strikingly young age of new variant Creutzfeldt-Jacob disease (vCJD) cases remains unexplained. Age dependent susceptibility to infection has been put forward, but differential dietary exposure to contaminated food products in the UK population according to age and sex during the bovine spongiform encephalopathy (BSE) epidemic may provide a simpler explanation. METHODS Using re...

Gene Set Enrichment Analysis (GSEA) is a basic tool for genomic data treatment. Its test statistic is based on a cumulated weight function, and its distribution under the null hypothesis is evaluated by Monte-Carlo simulation. Here, it is proposed to subtract to the cumulated weight function its asymptotic expectation, then scale it. Under the null hypothesis, the convergence in distribution of...

Determining the effectiveness of XML retrieval systems is crucial for improving information retrieval from XML document collections. Traditional effectiveness measures do not address the problem of overlap in the recall-base. At the Initiative for the Evaluation of XML retrieval (INEX), extended cumulated gain (XCG) was developed to address overlap. It works by comparing the cumulated score of ...

Exposure to ultrafine particles (UFPs) from vehicle exhaust has been related to risk of cardiovascular and pulmonary disease and cancer, even though exposure assessment is difficult. We studied personal exposure in terms of number concentrations of UFPs in the breathing zone, using portable instruments in six 18-hr periods in 15 healthy nonsmoking subjects. Exposure contrasts of outdoor polluti...

The purpose of this study was to follow-up the variation of pro-/antioxidant status throughout a whole season in elite professional soccer players from the French league (n=19, 18.3±0.6 years) and to examine a possible link between these variations and training load. 5 time points (T1, T2, T3, T4, T5) were proposed to surround crucial periods of training during the whole season: the pre-season ...