Along with development of modern imaging techniques in cancer biology, cryosurgery is emerging as minimally invasive surgical technique in treatment of some specific tumors (kidney, breasts, and bones, liver). Colon polyps/cancers are second largest cancers among humans with high death rate. They are diagnosed under various endoscopic methods/CT/MRI scans, and treated with surgical resection. H...

BACKGROUND Cryosurgery is an adjuvant surgical technique for the treatment of benign aggressive, low-grade malignant and metastatic tumors of long bones. It has been used rarely to treat sacral tumors, mainly because of potential damage to nerves, blood vessels, and intrapelvic organs. The authors described their experience with this procedure and provided medium and long-term follow-up results...

* Corresponding author: [email protected] ABSTRACT Basel cell carcinoma (BCC) is the most common human skin malignancy. Its incidence has increased significantly in Australia, Europe and North America over the past decade. A number of modalities are currently used for treatment of BCC, including cryosurgery which offers a potential for high cure rate, low cost, minimal bleeding and good cosmetic...

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In this study, we determined the number of peripheral blood circulating tumor cells (CTCs) pre- and post-cryosurgery in patients with colorectal cancer liver metastasis as a reference for understanding the relevance of any changes to the efficacy of cryosurgery. CTC numbers and CTC-related gene expression were measured in the peripheral blood of 55 patients with colorectal liver metastasis at 1...

OBJECTIVE Cryosurgery is a minimally invasive cancer treatment that uses liquid nitrogen or supercooled argon to freeze and destroy tumors. To achieve complete ablation of the prostate, we have developed a computer program that can determine treatment effects by calculating iceball formation. This is based on a three-dimensional (3D) model of the patient's prostate constructed from ultrasound i...

Cryosurgery (CS) has been used on patients with clinically localized PCa for more than 10 years. However, clinical studies evaluating its effectiveness and safety have reported conflicting results. This systematic assessment was performed to obtain comprehensive evidence regarding the potential benefits and safety of CS compared with those of radiotherapy (RT) and radical prostatectomy (RP), re...

UNLABELLED A new conceptual modality for nano-cryosurgical ablation of tumors is proposed in this article. The main strategy is to apply MgO nanoparticles (NPs), which are nontoxic, biodegradable, and have few side-effects on the human body, to mediate the freezing procedure effectively. Detailed investigation via animal experiments and nucleation analysis demonstrated that delivery of MgO NPs ...