BACKGROUND Anti-TNF agents are often reserved for patients with severe Crohn's disease (CD). AIMS We explored the predictive value of baseline disease activity and C-reactive protein (CRP) for disease course, adalimumab efficacy for remission (induction and maintenance) in patients with moderate and severe CD, and adalimumab efficacy in moderate CD by CRP category. METHODS Post hoc analyses...

Introduction. The use of non-invasive methods for examining patients with endoscopic remission can be useful in identifying the need interventions and assessing disease activity over time.
 Materials methods. We analyzed two hundred thirty medical histories children Crohn’s (CD) who were examined treated at National Medical Research Center Children’s Health. relationship between CD simple ...

BACKGROUND Fatigue is common in Crohn's disease (CD) and ulcerative colitis (UC). Data on fatigue in newly diagnosed patients are unavailable. AIM To report prevalence of fatigue in newly diagnosed CD and UC patients and examine its association with health-related quality of life (HRQOL), depression and disability. METHODS The Ocean State Crohn's and Colitis Area Registry (OSCCAR) is a stat...

Clinical characteristics of the cohort of 150 patients with inflammatory bowel diseases, ulcerative colitis (UC) and Crohn's disease (CD), Vukovarsko-Srijemska County, Croatia, were retrospectively assessed. UC was clinically presented with frequent passage of bloody, slimy stools, while preferential symptoms of CD were fever, anemia and severe weight loss, differences reflecting longer duratio...

Crohn's disease (CD) is a chronic inflammatory bowel disease that can be diagnosed at any age. There are two major patient groups based on diagnosis of this disease, before or after the age of 20 (juvenile/adolescent or adult), with disease progression in adults usually milder than in juvenile CD patients. Immune mechanisms have been suggested to play an important role in CD pathogenesis, with ...

celiac disease (cd) is an immune-mediated disorder resulting in nutrient malabsorption now thought to have a prevalence of 1:100 in the iranian population.symptoms of cd are included diarrhea, abdominal pain, steatorrhea, bloating, cramps, flatulence, weight loss, weakness and short stature. in addition to presenting symptoms, patients are also at increased risk of metabolic bone disease, lymph...

BACKGROUND Mucosal healing (MH) is a vital early endpoint in management of Crohn's disease (CD). MH depends on endoscopic assessment and there is increasing interest in non-invasive proxies, Pediatric Crohn's Disease activity Index (PDCAI), C-reactive protein (CRP) and fecal calprotectin (FC). These proxies must be validated against endoscopic disease activity (SES-CD) at diagnosis and after in...

Hepatic Abscesses have been reported in association with Crohn's disease (CD). They either occur as a complication of known CD, or as in this case, are the presentation of undiagnosed disease. The management of the CD associated with liver abscesses is a matter of debate. We report a case of CD presenting with hepatic abscesses, review the literature and discuss the management options.