Chlamydia pneumoniae has been associated to atherosclerotic cardiovascular diseases. The aim of our study was to characterize, for the first time, a C. pneumoniae strain isolated from the gingival crevicular fluid of a patient with chronic periodontitis, described as a risk factor for cardiovascular diseases. C. pneumoniae isolate was characterized and compared to the respiratory AR-39 strain b...

INTRODUCTION A study is made of the usefulness of cytokines (such as interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10) and interleukin-12 (IL-12)) as markers of periimplant disease (mucositis and periimplantitis). An increase in the levels of these cytokines in dental implant crevicular fluid may give rise to a lack of osteointegration, bone loss or implant failure. OBJECTIVE...

AIM The aim of this study was to assess the levels and diagnostic accuracy of a set of potential biomarkers of periodontal tissue metabolism in gingival crevicular fluid (GCF) from patients with chronic periodontitis (CP) and asymptomatic apical periodontitis ( AAP). MATERIALS AND METHODS Thirty one GCF samples from 11 CP patients, 44 GCF samples from 38 AAP patients and 31 GCF samples from 1...

Tobacco smoking is regarded as one of the most significant risk factors in the development and progression of periodontal disease. Studies have shown an altered host antibody response to antigenic challenge in smokers with periodontitis. The study was undertaken to estimate the gingival crevicular fluid (GCF) immunoglobulin G,A,M (IgA, IgG and IgM) levels in smokers and non smoker with periodon...

The aim of this study was to review the proinflammatory cytokine profiles in the peri-implant crevicular fluid (PICF) of patients with peri-implantitis (PI). Databases were explored from 1994 up to and including July 2010 using various combinations of the following keywords: "cytokine", "crevicular fluid", "implant", "inflammation", "peri-implantitis" and "periodontitis". The eligibility criter...

OBJECTIVES The aim of this study was to compare microbiological, histological, and mechanical findings from tissues around osseointergrated dental implants in patients who had undergone tumour resection and subsequent bone grafting with non bone grafted patients without a history of oral cancer and to develop an effective tool for the monitoring of the peri-implant tissues. A third aim was to a...

It is generally accepted that peri-implantitis is caused by a bacterial challenge to the implantbearing soft and hard tissues. A few studies have focused on the investigation of peri-implant crevicular fluid (PICF) flow rate and their relationship with the peri-implant condition. Hence, the aim of the present study was to assess if PICF flow rate can be further studied as a possible objective d...

OBJECTIVE To determine the oral status, salivary flow rate, Candida carriage in saliva, and prevalence of Candida albicans colonization in several areas of the mouth in patients with primary and secondary Sjögren's syndrome as opposed to those of healthy subjects. STUDY DESIGN Thirty-seven patients with Sjögren's syndrome (SS), [14 patients with primary SS (SS-1) and 23 patients with secondar...

BACKGROUND Cytokines are suggested to play a role in periodontitis. OBJECTIVES To determine and compare the levels of Interleukin-1 beta (IL-1β) and Tumor necrosis factor alpha (TNF-α) in gingival crevicular fluid (GCF) samples amongst healthy individuals and those with chronic periodontitis. Further to compare the GCF cytokine levels in three genotype classes defined by the respective gene p...

Aim To evaluate the effectiveness on tissue response of the new nutritional supplement made of oligomeric proanthocyanidins in induced gingivitis after 21 days of use. Material and Methods A prospective, double-blind, randomized, controlled clinical trial was carried out on 20 patients; it is divided into an experimental group and a control group after fulfilling the selection criteria. Patie...