background: heavy exercise cause muscle damage associated with production of inflammatory agents. the purpose of present study was to determine the effect of acute and 14-day coenzyme q10 supplementation on inflammatory, blood lactate and muscle damage in male middle-distance runners.   methods : eighteen male middle-distance runners in a randomized and quasi experimental study were allocated i...

PURPOSE To determine if timing of a supplement would have an effect on muscle damage, function and soreness. METHODS Twenty-seven untrained men (21 +/- 3 yrs) were given a supplement before or after exercise. Subjects were randomly assigned to a pre exercise (n = 9), received carbohydrate/protein drink before exercise and placebo after, a post exercise (n = 9), received placebo before exercis...

this study intended to compare the effect of consuming creatine and mixed creatine-carbohydrate supplementations on the anaerobic power and cellular damage indices (ck, ldh) in males aged between 15 and 18 in the city of kouhrang. for this purpose, 36 subjects (mean age 16.42±0.90 yrs, weight 54.85±9.96 kg, and height 167.75±8.28 cm) were selected by available method. first, blood samples were ...

BACKGROUND Eccentric exercise-induced damage leads to reductions in muscle force, increased soreness, and impaired muscle function. Creatine monohydrate's (Cr) ergogenic potential is well established; however few studies have directly examined the effects of Cr supplementation on recovery after damage. We examined the effects of Cr supplementation on muscle proteins and force recovery after ecc...

INTRODUCTION Quantities of various anabolic/androgenic steroids have been found in dietary supplements without their presence being disclosed on the label. The aim of this study was to quantify the excretion patterns of the diagnostic metabolites, 19-norandrosterone (19-NA), and 19-noretiocholanolone (19-NE) after ingestion of small doses of 19-nor-4-androstene-3,17-dione (19-norandrostenedione...

The purpose of this study was to determine whether resistance exercise performance and postexercise muscle damage were altered when consuming a carbohydrate and protein beverage (CHO-PRO; 6.2% and 1.5% concentrations). Thirty-four male subjects (age: 21.5 +/- 1.7 years; height: 177.3 +/- 1.1 cm; weight: 77.2 +/- 2.2 kg) completed 3 sets of 8 repetitions at their 8 repetition maximum to volition...

BACKGROUND Berberine, an alkaloid with both glucose- and cholesterol-lowering action, is also characterized by an anti-diarrheal effect. Consequently, berberine-based therapies are recommended for diabetic patients with irritable bowel syndrome (IBS) or gut discomfort caused by metformin. AIM As the anti-glycemic and cholesterol-lowering action of berberine is improved by co-administration wi...

creatine exerts beneficial effects on a variety of pathologies in which energy metabolism and oxidative stress play an etiological role. creatine supplements have shown beneficial effects on neurological disorders including parkinson's disease, huntington's disease, amyotrophic lateral sclerosis, alzheimer's disease and stroke. however, the potential benefits of creatine for pati...

The appearance in print of the present volume of the “Subcellular Biochemistry” Series entitled “Creatine and Creatine Kinase in Health and Disease”, edited by Gajja S. Salomons and Markus Wyss, seems entirely timely. The importance and physiological significance of creatine kinase (CK) as well as the pleiotropic effects of creatine (Cr) and phosphocreatine (PCr) in health and disease have been...