نتایج جستجو برای: crack cocaine
تعداد نتایج: 39318 فیلتر نتایج به سال:
Cocaine and its principal metabolite, benzoyl ecgonine, were isolated from the urine of four hospitalized children who had been exposed to the smoke of freebase cocaine ("crack") used by their adult caretakers. Two of the children had transient neurological symptoms (drowsiness and unsteady gait) and two had seizures whose cause could not be determined by laboratory investigation. Passive cocai...
Cocaine, derived from the shrub Erythroxylon coca, was both chemically extracted and reported to be psychotogenic in 1859. Included in the original formulation of ‘Coca-Cola’, it was declared illegal under the Harrison Act of 1914. It has been used as a local anaesthetic and in analgesic cocktails. In one study, the main routes of administration were: smoking, 40%; intranasal, 32%; and injectin...
BACKGROUND While crack cocaine has been associated with elevated sexual risks and transmission of HIV/STIs, particularly in the context of street-based sex work, few empirical studies have examined correlates of direct sex-for-crack exchanges. This study longitudinally examined the correlates of sex-for-crack exchanges and associated effects on sexual risk outcomes among street-based female sex...
US Federal sentencing guidelines punish possession of crack cocaine very differently from powder cocaine, based partially upon the assumption that crack users engage more frequently in criminal behavior to pay for their habit. This article analyzed frequent users (those who have used at least 15 of the last 30 days) of crack with subgroups of less frequent hard drug users in terms of various in...
AIMS To investigate whether a stimulant- and alcohol-focused brief motivational intervention induces positive behaviour change among young, regular users of MDMA ('ecstasy'), cocaine powder and crack cocaine. DESIGN AND MEASUREMENTS A randomized trial of the intervention versus a control group who received written health risk information materials only. All participants completed a baseline s...
Smoking crack cocaine involves the inhalation of cocaine and its pyrolysis product, anhydroecgonine methyl ester (AEME). Although there is evidence that cocaine is neurotoxic, the neurotoxicity of AEME has never been evaluated. AEME seems to have cholinergic agonist properties in the cardiovascular system; however, there are no reports on its effects in the central nervous system. The aim of t...
An increase in the use of cocaine and crack in several parts of Europe has raised the question whether this trend is similar to that of the USA in the 1980s. However, research in the field of cocaine use in Europe has been only sporadic. Therefore, a European multi-centre and multi-modal project was designed to study specific aspects of cocaine and crack use in Europe, in order to develop guide...
A 31-year-old female presented with acute onset shortness of breath and chest pain. She had a past medical history of cocaine abuse and agreed that she used cocaine 2 days prior to presentation. On admission, her vitals included Blood Pressure of 160/70, Heart Rate—110, Respiratory Rate—36 with oxygen saturation of 78%. Chest X-ray showed some interstitial opacities. CT scan of the chest was pe...
In Australia, the lifetime use of cocaine is rising, with 3% of the population aged over 14 using cocaine in 1991, increasing to 4.5% in 1998, and cocaine use accounting for 10% of all deaths secondary to illicit drug use in 1998. Cocaine is prepared from the leaves of the plant Erythroxylon coca, and is available as cocaine hydrochloride (a water-soluble powder or granule which can be taken or...
Crack cocaine use carries high costs for society, particularly in terms of increased crime. The tools of modern neuroscience may be able to reduce demand by addressing altered brain circuitry of individuals suffering from severe cocaine use disorder. Here, we review several rehabilitative strategies, including pharmacotherapies targeting neurotransmitter systems, immunotherapies that block coca...
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