Cortisol potentiated norepinephrine (NE)-mediated contractions in ovine uterine arteries (UA). We tested the hypothesis that cortisol regulated alpha(1)-adrenoceptor-mediated pharmacomechanical coupling differentially in nonpregnant UA (NUA) and pregnant UA (PUA). Cortisol (10 ng/ml for 24 h) significantly increased contractile coupling efficiency of alpha(1)-adrenoceptors in NUA, but increased...

Evidence suggests that previous trauma reduces the cortisol response to subsequent stressors. We examined the relation of this response to intrusive memory, and the potential moderating roles of sympathetic reactions. Pre-existing trauma-related factors and the cardiac defense response were assessed before 58 healthy participants viewed a trauma film. Salivary cortisol and alpha-amylase (sAA) w...

Figure 3. Bland-Altman plot between total serum cortisol and free serum cortisol (57 patients). Limits of agreement, 2 33.966 to 2 4.596; mean difference, 2 19.281; 95% CI, 2 21.229 to 2 17.333; range, 2.495-25.825; Pitman test r , 2 0.981; P 5 0.001. diffi cult and time consuming (see the “Discussion” section in original article 1 ). Even more important is the observation that the degree of ag...

Background and Aim: Benign migratory glossitis, or geographic tongue, is usually an asymptomatic inflammatory disorder of unknown etiology that affects the epithelium of the tongue. Among the etiologic factors proposed, emotional causes were suspected by several investigators. The objective of this study was to evaluate the anxiety and cortisol level in patients with geographic tongue compared ...

A procedure previously used for sex steroids was adapted to extract free cortisol and cortisone from water samples taken from rainbow trout Oncorhynchus mykiss tanks. Both corticosteroids could be readily detected by radioimmunoassay (RIA), with cortisol being predominant. All stages of the sampling, extraction and RIA procedure were validated for cortisol. An intermittent problem with poor rep...

The objective of this study was to examine the effect of anabolic steroids (testosterone, T; dihydrotestosterone, D; trenbolone acetate, B; and zeranol, Z) on cortisol synthesis by cultured bovine adrenocortical cells. Adrenal glands were obtained from slaughter-aged steers (n = 4). Cortical cells were isolated and their steroidogenic capacity was examined. They were plated in multiwell culture...

Objective: To investigate the relationship between cortisol levels, pain intensity and negative mood in chronic pain patients participating in a multidisciplinary pain management programme. Patients: Eighteen chronic pain patients collected saliva samples over several days both directly before and after attending a four-week multidisciplinary pain management programme. Outcome measures: Saliva ...

OBJECTIVES The aim of this paper is to test the influence of long-term application of the low-frequency magnetic fields in magnetotherapy and magnetostimulation on cortisol secretion in men. MATERIALS AND METHODS Patients were divided into three groups: 16 men underwent magnetotherapy and 20 men (divided into two groups) underwent magnetostimulation. Magnetotherapy - 2 mT induction, 40 Hz, bi...

Chronic pain is often equated with chronic stress yet the relationship between chronic pain and hypothalamic-pituitary-adrenal (HPA) axis activity is poorly understood. The objective of this study was to examine diurnal functioning of the HPA axis in patients with clinically defined non-inflammatory chronic pain syndrome (CPS) compared to controls. The sample consisted of 37 adults with CPS and...