Low-frequency peripheral electrical stimulation using a matrix electrode (PEMS) modulates spinal nociceptive pathways. However, the effects of this intervention on cortical oscillatory activity have not been assessed yet. The aim study was to investigate low-frequency PEMS (4 Hz) in different brain states healthy pain-free participants. In experiment 1, compared sham stimulation. 2, motor image...

Transcranial Direct-Current Stimulation (tDCS) is a non-invasive form of brain stimulation similar to transcranial magnetic stimulation, but instead of using magnets, it uses a lowintensity, constant current applied through scalp electrodes. Generally, anodal stimulation induces an increase of cortical excitability, whereas cathodal stimulation decreases cortical excitability, with effects that...

We studied somatosensory evoked fields elicited by mechanical vs. electrical stimuli to index finger of healthy subjects. Mechanical stimulation was index pulp compression and decompression by using non-magnetic mechanical stimulator. Electrical stimulation was three times of sensory threshold and delivered to index pulp by using ball-shaped electrodes. Mechanical/electrical-stimuli evoked cont...

Recent studies have shown that the corticofugal system systematically modulates and improves subcortical signal processing in the frequency, time and spatial domains. The present study examined corticofugal modulation of amplitude sensitivity of 113 corticofugally inhibited neurons in the central nucleus of the inferior colliculus (IC) of the big brown bat, Eptesicus fuscus. Cortical electrical...

The impact of traumatic spinal cord injury on structural integrity, cortical reorganization and ensuing disability is variable and may depend on a dynamic interaction between the severity of local damage and the capacity of the brain for plastic reorganization. We investigated trauma-induced anatomical changes in the spinal cord and brain, and explored their relationship to functional changes i...

BACKGROUND Cortical modulation is likely to be involved in the various therapeutic effects of deep brain stimulation (DBS). However, it is currently difficult to predict the changes of cortical modulation during clinical adjustment of DBS. Therefore, we present a novel quantitative approach to estimate anatomical regions of DBS-evoked cortical modulation. METHODS Four different models of the ...