نتایج جستجو برای: cortical dysplasia

تعداد نتایج: 133004  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2000
W J Zhu S N Roper

Cortical dysplasia has a strong association with epilepsy in humans, but the underlying mechanisms for this are poorly understood. In utero irradiation of rats produces diffuse cortical dysplasia and neuronal heterotopia in the neocortex and hippocampus. Using in vitro neocortical slices, whole-cell patch-clamp recordings were obtained from pyramidal neurons in dysplastic cortex and control neo...

Journal: :Journal of neuropathology and experimental neurology 2007
Maria Thom Lillian Martinian Arjune Sen W Squier Brian N Harding J H Cross William Harkness Andrew McEvoy Sanjay M Sisodiya

Balloon cells (BCs) are the pathologic hallmark of focal cortical dysplasia type IIB, a common cause of pharmacoresistent epilepsy. Expression of markers of cell immaturity and of the proliferation marker minichromosome maintenance protein 2 (mcm2) have been previously shown in BCs, suggesting that these cells might represent a pool of less-differentiated cells licensed for replication. An alte...

Journal: :Journal of Neurology, Neurosurgery & Psychiatry 2003

Journal: :Physical review letters 2005
Thomas H van den Berg Stefan Luther Daniel P Lathrop Detlef Lohse

In Taylor-Couette flow the total energy dissipation rate and therefore the drag can be determined by measuring the torque on the system. We do so for Reynolds numbers between Re=7 x 10(4) and Re=10(6) after having injected (i) small bubbles (R=1 mm) up to a volume concentration of alpha=5% and (ii) buoyant particles (rhop/rhol=0.14) of comparable volume concentration. In case (i) we observe a c...

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