BACKGROUND Polyetheretherketone (PEEK) has a wide range of clinical applications but does not directly bond to bone. Bulk incorporation of osteoconductive materials including hydroxyapatite (HA) into the PEEK matrix is a potential solution to address the formation of a fibrous tissue layer between PEEK and bone and has not been tested. QUESTIONS/PURPOSES Using in vivo ovine animal models, we ...

Introduction: Diagnosis of lesions and bone defects is very important and there is a lack of substantial studies on the most appropriate method for bone defect measurement. Hence, the aim of this study is to evaluate the accuracy of multi-slice computed tomography (MSCT) and cone-beam computed tomography (CBCT) in the diagnosis of mandibular bone defects present in sheep. Material & Methods: T...

Bone cancer is rare in adults, the most affected persons by this disease are young people and children. The common treatments for bone surgery, chemotherapy, targeted therapies; however, all of them have side-effects that decrease patient’s quality life. Thermotherapy one promising cancer; its main goal to increase tumor temperature kill cancerous cells. Although some micro-coaxial antennas bee...

Background: Melorheostosis has been discussed infrequently in the nuclear medicine literature. A 25-year-old female patient presented with a one-year history of b:union: pain, sclerotic change and skin pigmentation on the left big toe interphalangeal joint. Ulceration, poor healing and hyperkeratoses of the wound were noted post debridement. The plain film of the left foot incidentally showed m...

INTRODUCTION There is currently no cure for the skeletal dysplasia osteogenesis imperfecta (OI), a debilitating disease that occurs in approximately 1 in every 20,000 human births. OI is caused by a genetic mutation that results in brittle bones and many fractures. In a mouse model of the disease, oim, we have characterized bone structure using X-ray microtomography, and found that oim bone has...

orthodontic miniscrews are widely used as temporary anchorage devices to facilitate orthodontic movements. miniscrew loosening is a common problem, which usually occurs during the first two weeks of treatment. macrodesign can affect the stability of a miniscrew by changing its diameter, length, thread pitch, thread shape, tapering angle and so on. in this study, a 3-d finite element analysis wa...