Fig. 1. Transverse midesophageal plane at 458, demonstrating the short axis of the aortic valve in diastole. The ruptured aneurysm of the right coronary sinus protrudes into the right atrium just above the tricuspid valve producing the characteristic ‘windsock’ appearance described in textbooks. Colour-flow Successful surgical repair of a ruptured sinus of Valsalva aneurysm was performed in a 3...

We report the case of a rare anomaly of the right coronary artery (RCA) arising from the left aortic sinus, having a single ostium with the left coronary artery, associated with documented episodes of inferior ischemia, in which surgical treatment with a right internal thoracic artery to RCA bypass graft and the corresponding ligation provided greater stability to the coronary blood flow and go...

OBJECTIVES To develop a nonlethal model of hyperdynamic sepsis, and to measure vital organ blood flows in this setting. DESIGN Randomized crossover animal study. SETTING Animal laboratory of university-affiliated physiology institute. SUBJECTS Seven Merino cross sheep. INTERVENTIONS Surgical implantation of transit-time flow probes around sagittal sinus and circumflex coronary, superior...

The renin-angiotensin system regulates the vascular fibrinolytic balance. In the human forearm vasculature, angiotensin-converting enzyme (ACE) inhibitors (ACE-Is) increase the release of t-PA through endogenous bradykinin. We tested the hypothesis that ACE inhibition and sex modulate the endogenous coronary release of tissue plasminogen activator (t-PA) in hypertensive patients. Seventy-three ...

Effects of change in PaCO2 on systemic and coronary haemodynamics and on coronary sinus blood-gases have been studied in 10 open-chested dogs in which the lungs were ventilated with 0.8% halothane in oxygen, before and after administration of oxprenolol 0.3 mg kg-1 i.v. The hyperdynamic response of the circulation to hypercapnia was only marginally reduced after oxprenolol (cardiac output incre...

Cardiac lymph in dogs was used to study the metabolism and state of the myocardium during extracorporeal circulation and various additional procedures. Changes in the flow characteristics, cdor and pH of lymph were noted, and corresponding samples of cardiac lymph and coronary sinus blood were analyzed for lactate concenlmtion. Ventricular fibrillation led to higher lactate levek when compared ...

BACKGROUND Gender-specific differences in cardiovascular risk are well known, and current evidence supports an existing role of endothelium in these differences. The purpose of this study was to assess non invasively coronary endothelial function in male and female young volunteers by myocardial blood flow (MBF) measurement using coronary sinus (CS) flow quantification by velocity encoded cine ...

Previous studies have suggested that (1) nitroglycerin causes vasodilatation by interacting with sulfhydryl groups in vascular smooth muscle, thereby activating guanylate cyclase and increasing the intracellular concentration of cyclic GMP, and (2) N-acetylcysteine, a source of sulfhydryl groups, potentiates the peripheral vasodilatory effect of nitroglycerin. This study was performed to explor...

OBJECTIVE To analyze the correlation between local interleukin-6 (IL-6) levels in different parts of blood vessel and the record of Thrombolysis in Myocardial Infarction (TIMI) frame count (TFC) after myocardial ischemia-reperfusion (IR) model. MATERIALS AND METHODS Establishment of IR model in Yorkshire pigs, the pigs were divided into two groups (n=6). Experiment group pigs were administrat...