BACKGROUND A return toward toward photorefractive keratectomy has occurred due to better corneal stability and fewer corneal flap complications; however, pain remains a major drawback of the procedure. Currently, clinical pain control measures focus on the administration of pain medications, which may delay corneal epithelial healing and has, occasionally, led to serious corneal toxicity. OBJ...

INTRODUCTION The field of refractive surgery continues to evolve amid continued concerns as to which surgical technique minimizes the risk of inducing ectasia. PURPOSE To compare clinical outcomes between PRK, LASEK and Epi-LASIK in moderately to highly myopic eyes (-4.00 D to -8.00 D). MATERIALS AND METHODS A retrospective chart review of 100 PRK eyes, 100 LASEK eyes (with alcohol) and 97 ...

PURPOSE To report corneal decompensation in 3 patients with recessive cornea plana. METHODS Retrospective case series. RESULTS An adult and two children (all unrelated) with clinical recessive cornea plana had gradual decrease in vision. Ophthalmic examination revealed corneal decompensation (stromal thickening and haze without epithelial changes) in the 3 patients. Diagnostic DNA sequencin...

Gene therapy to the cornea can potentially correct inherited and acquired diseases of the cornea. Factors that facilitate corneal gene delivery are the accessibility and transparency of the cornea, its stability ex vivo and the immune privilege of the eye. Initial corneal gene delivery studies characterized the relationship between intraocular modes of administration and location of reporter ge...

Laser in situ keratomileusis (LASIK) is an effective procedure to treat a wide range of myopia. The advantages of LASIK over photorefractive keratectomy (PRK) are rapid visual recovery, lower risk of corneal haze, greater regression of myopia, and less postoperative pain. However, LASIK requires more skillful surgical technique and more instrumentation than PRK. Thus, inaccurate and inadequate ...

Purpose. To evaluate the safety, efficacy, and predictability of photorefractive keratectomy (PRK) on the corneal flap for correction of residual myopia following myopic laser in situ keratomileusis (LASIK). Patients and Methods. A retrospective study on eyes retreated by PRK on the corneal flap for residual myopia after LASIK. All eyes had no enough stroma after LASIK sufficient for LASIK enha...

PURPOSE To describe the microscopic corneal and conjunctival findings in patients with Fabry disease (FD) related keratopathy by using in vivo confocal microscopy. DESIGN Prospective observational case series. METHODS Twelve eyes of six patients affected by Fabry disease, belonging to two different families, underwent in vivo confocal microscopic examination. Corneal and conjunctival morpho...